Impact of Anesthesia, Positive Pressure Ventilation and Modality of Imaging on the Echocardiographic Assessment of the Severity of Aortic Regurgitation

NCT ID: NCT06835946

Last Updated: 2025-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-01

Study Completion Date

2027-04-01

Brief Summary

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The goal of this observational study is to assess the impact of imaging modality (trans-thoracic echo (TTE) vs trans-esophageal echo (TEE)), anesthesia and positive pressure ventilation on the grading of aortic insufficiency.

Patients scheduled for cardiac surgery and in whom a TEE is going to be performed intra-operatively will be enrolled. The grading of the aortic insufficiency will be compared between a TTE performed immediately before the induction of general anesthesia end the TEE performed after induction of general anesthesia.

Detailed Description

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Conditions

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Aortic Regurgitation Disease Aortic Insufficiency

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Adult patients scheduled for cardiac surgery with previously known aortic regurgitation of any grade

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Known aortic regurgitation of any grade
* Scheduled for a cardiac surgery procedure during which a trans-esophageal echo is planned.

Exclusion Criteria

* Non sinus rhythm
* Mitral regurgitation more than mild.
* Pre-operative critical state (according to the definition of the EuroSCORE II)
* Presence of a prosthetic aortic valve
* Contra-indication to trans-esophageal echo
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Liege

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre Hospitalier Universitaire de Liège

Liège, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Alan Houven, MD

Role: CONTACT

+3243237655

Facility Contacts

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Alan Houven, MD

Role: primary

Other Identifiers

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ANESTIAO

Identifier Type: -

Identifier Source: org_study_id

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