Assessment of Diastolic Function in High Risk Patients Undergoing Major Vascular Surgery

NCT ID: NCT03534440

Last Updated: 2020-07-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-07-01

Study Completion Date

2020-01-30

Brief Summary

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Patients scheduled for Thoracic Endovascular Aortic Repair (TEVAR) surgery will have transthoracic echocardiography evaluation of left ventricle diastolic function during the perioperative period.

Detailed Description

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Patients undergoing TEVAR surgery are a high risk group of developing perioperative cardiovascular complications.

Left ventricle diastolic dysfunction is common in this group of patients because of the prevalence of risk factors: \> 60 years old, hypertension, smoking history and diabetes.

Because of many predisposing factors that occur during the surgery: stress respond, fluid shifts, anaesthesia and mechanical ventilation. Deterioration of the diastolic function is likely to occur in perioperative period

In this study, the investigators will evaluate change in left ventricle diastolic function as a marker for early detection of a myocardial failure in patients scheduled for an elective TEVAR surgery. The examination will be performed preoperatively, shortly after the surgery and 24 hours after the surgery.

Aim: The aim of the study is to evaluate the diastolic function of left ventricle in perioperative period after high risk surgery. This may provide a valuable information in preoperative risk stratification and postoperative therapy guidance.

Conditions

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Diastolic Dysfunction Heart Failure Aneurysm Aortic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* scheduled TEVAR
* \>60 years old

Exclusion Criteria

* Atrial fibrillation or other non-sinus rhythms
* Atrioventricular blocks
* Heart rate change more than 25% postoperatively
* Not adequate transthoracic view
* Postoperative shock
* Sepsis
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Warsaw

OTHER

Sponsor Role lead

Responsible Party

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Mateusz Zawadka

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Medical University Of Warsaw

Warsaw, Mazovian, Poland

Site Status

Countries

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Poland

Other Identifiers

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DD-TEVAR-2018

Identifier Type: -

Identifier Source: org_study_id

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