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Respiratory Variations of the Diameter of Superior Vena Cava for Predicting Fluid Responsiveness After Cardiac Surgery

NCT ID: NCT03393897

Last Updated: 2018-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

56 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-03

Study Completion Date

2018-10-31

Brief Summary

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In a recent study (Vignon 2017), respiratory variations of the diameter of superior vena cava had a greater diagnostic accuracy than pulse pressure variations and inferior vena cava respiratory variations in 540 medical and surgical ICU patients. But this indicator has not been investigated yet in cardiac surgery. The investigator aim to study respiratory variations of superior vena cava for predicting fluid responsiveness after cardiac surgery.

In post-operative cardiac surgery patients with hemodynamic failure, the investigator will measure respiratory vena caval variations with TEE (Trans oesophageal echocardiography). Then, the investigator will evaluate fluid responsiveness after a fluid challenge (Trendelenburg).

A ROC curve will be constructed in order to assess the optimal sensitivity and specificity of this parameter.

Detailed Description

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Conditions

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Transesophageal Echocardiography Vena Cava Superior

Keywords

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fluid responsiveness cardiac surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Hemodynamic instability with hypotension

Trans oesophageal echocardiography

Intervention Type OTHER

Transoesophageal echocardiography : it's a standard practice for this patient

Trendelenburg test

Intervention Type OTHER

Trendelenburg test : it's a standard practice for this patient

Interventions

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Trans oesophageal echocardiography

Transoesophageal echocardiography : it's a standard practice for this patient

Intervention Type OTHER

Trendelenburg test

Trendelenburg test : it's a standard practice for this patient

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Hemodynamic instability with hypotension,
* Low cardiac output or norepinephrine requirements in the first 6 post-operative hours.

Exclusion Criteria

* TEE (Trans oesophageal echocardiography) contra-indication
* Trendelenburg contra-indication
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Olivier PEYROUSET, MD

Role: PRINCIPAL_INVESTIGATOR

CHU SAINT-ETIENNE

Locations

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Centre Hospitalier Universitaire de Saint Etienne

Saint-Etienne, , France

Site Status

Countries

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France

Other Identifiers

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IRBN662017

Identifier Type: -

Identifier Source: org_study_id