Detection of Right Ventricular Dysfunction by Portal Vein Doppler After Cardiac Surgery

NCT ID: NCT04890860

Last Updated: 2023-03-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-15

Study Completion Date

2022-08-11

Brief Summary

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Right ventricular (RV) failure after cardiac surgery is associated with morbidity and mortality, but is hard to diagnose with conventional echocardiographic means. RV dysfunction may be associated with hepatic congestion, which may have an effect on portal veinous flow, but this has not been extensively. The investigators aimed determine whether an increased pulsatility in the portal venous flow was associated with RV dysfunction, after cardiac surgery at risk of RV dysfunction: mitral and tricuspid valve procedures.

Detailed Description

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In cardiac surgical patients, RV dysfunction is associated with organ hypoperfusion and venous congestion leading to increased morbidity and mortality.

Non-invasive methods used to assess RV function are 2D-echocardiographic measurement of tricuspid annular plane systolic excursion (TAPSE), RV ejection fraction (EF), RV fractional area change (FAC), 3D assessment of RV function, tissue Doppler assessment of velocities, and magnetic resonance imaging (MRI). Though MRI is the gold standard method to assess RV function, it cannot be used in the perioperative period.

In the present prospective observational study, The investigators investigated the association between the pattern of portal venous flow and RV function as assessed by echocardiography in the postoperative period.

Conditions

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Postoperative Complications Heart Diseases Heart Failure Heart Valve Diseases

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Adults patients undergoing mitral and / or tricuspid valve surgery with cardiopulmonary bypass.

Group Type EXPERIMENTAL

cardiac surgery involving mitral or tricuspid valve repair procedure, with cardiopulmonary bypass

Intervention Type OTHER

cardiac surgery involving mitral or tricuspid valve repair procedure, with cardiopulmonary bypass

Interventions

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cardiac surgery involving mitral or tricuspid valve repair procedure, with cardiopulmonary bypass

cardiac surgery involving mitral or tricuspid valve repair procedure, with cardiopulmonary bypass

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* More than 18 years old
* Ability to provide an informed consent
* Planned mitral and / or tricuspid valve surgery under cardiopulmonary bypass.

Exclusion Criteria

* Insufficient echogenicity
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CMC Ambroise Paré

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CMC Ambroise Paré

Neuilly-sur-Seine, , France

Site Status

Countries

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France

References

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Haddad F, Couture P, Tousignant C, Denault AY. The right ventricle in cardiac surgery, a perioperative perspective: II. Pathophysiology, clinical importance, and management. Anesth Analg. 2009 Feb;108(2):422-33. doi: 10.1213/ane.0b013e31818d8b92.

Reference Type BACKGROUND
PMID: 19151265 (View on PubMed)

Haddad F, Couture P, Tousignant C, Denault AY. The right ventricle in cardiac surgery, a perioperative perspective: I. Anatomy, physiology, and assessment. Anesth Analg. 2009 Feb;108(2):407-21. doi: 10.1213/ane.0b013e31818f8623.

Reference Type BACKGROUND
PMID: 19151264 (View on PubMed)

Denault AY, Beaubien-Souligny W, Elmi-Sarabi M, Eljaiek R, El-Hamamsy I, Lamarche Y, Chronopoulos A, Lambert J, Bouchard J, Desjardins G. Clinical Significance of Portal Hypertension Diagnosed With Bedside Ultrasound After Cardiac Surgery. Anesth Analg. 2017 Apr;124(4):1109-1115. doi: 10.1213/ANE.0000000000001812.

Reference Type BACKGROUND
PMID: 28151822 (View on PubMed)

Rudski LG, Lai WW, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K, Solomon SD, Louie EK, Schiller NB. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr. 2010 Jul;23(7):685-713; quiz 786-8. doi: 10.1016/j.echo.2010.05.010. No abstract available.

Reference Type BACKGROUND
PMID: 20620859 (View on PubMed)

Other Identifiers

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2020/08

Identifier Type: -

Identifier Source: org_study_id

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