Echocardiography as Risk-Assessment for Major Adverse Cardiac Events in Major Vascular Surgery Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

813 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-01-01

Study Completion Date

2022-03-21

Brief Summary

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Patient with coronary artery disease (CAD), heart failure and abnormal heart function undergoing major vascular surgery have a high associated high morbidity and mortality with myocardial infarction accounting for 33-50% of perioperative deaths. The prevalence of CAD in vascular surgery patients approaches 50%. Proper pre-procedure protocols to accurately assess patients and determine who may require further medical optimization prior to undergoing surgery help mitigate risk and improve outcomes. The investigators designed this study as a single center, retrospective cohort analysis to explore the association between ventricular (LV and RV function) and valvular (Aortic / Mitral / Tricuspid) function and expanded major adverse cardiac events (X-MACE).

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Detailed Description

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Conditions

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Left-Sided Heart Failure Right-Sided Heart Failure Heart Valve Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Left ventricular function

* Depressed LV function

1. LV ejection fraction \< 50%
2. LV systolic function; defined as mild / mod / sev decreased
3. LV diastolic function; defined as mild (g1 ) / mod (g2) / sev ( g3) decreased
* Normal LV function

No interventions assigned to this group

Right ventricular function

* Depressed RV function

a. RV systolic function defined as mild / mod / sev decreased
* Normal RV function

No interventions assigned to this group

Valvular lesions

* Moderate or severe valvular lesions

1. Aortic stenosis
2. Aortic regurgitation
3. Mitral stenosis
4. Mitral regurgitation
5. Tricuspid regurgitation
* Clinically normal valvular lesions

1. No valvular lesion
2. Mild stenosis / regurgitation of above mentioned lesions

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Major vascular surgery operation (e.g. CEA, open aortic repair, suprainguinal and infrainguinal bypasses, EVAR, TEVAR) captured in the UVA Vascular Quality Initiative database
* Echocardiography within two years of index operation