Diastolic Dysfunction and Atrial Fibrillation in CABG Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-03-31

Study Completion Date

2010-03-31

Brief Summary

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Left ventricular (LV) diastolic dysfunction is a common manifestation of heart disease that is responsible for significant morbidity and mortality.It is present when the ventricular filling is impaired as a result of delayed relaxation or decreased compliance. During Coronary artery bypass grafting (CABG) surgery, LV diastolic dysfunction is a frequent occurrence. Failure of the left ventricle to dilate normally causes an increase in LV filling pressure. Atrial fibrillation (AF) is a common complication after cardiac surgery affecting 20-30% of patients undergoing coronary revascularization procedures. AF is associated with significant morbidity and mortality and has been identified as a causative factor of increased length of both hospital and intensive care unit (ICU) stay after CABG surgery, resulting in increased resource utilization and medical care costs.The primary aim of this study is to determine if patients with preoperative diastolic dysfunction are exposed to higher risk of AF after coronary revascularization surgery.

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Detailed Description

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Conditions

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Heart Disease Atrial Fibrillation

Study Design

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Study Time Perspective

PROSPECTIVE

Interventions

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Diastolic measurements during TEE

Transesophageal echocardiography with diastolic measurements

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* scheduled for elective CABG or OPCAB surgery
* signed informed consent

Exclusion Criteria

* Patients with a history of previous heart surgery and/or undergoing valvular heart surgery.
* Patients with preoperative atrial fibrillation.
* Patients in whom TEE is contraindicated.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No