Impact of Left Atrial Function on Postoperative Atrial Fibrillation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-03-31

Study Completion Date

2008-05-31

Brief Summary

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We aimed to demonstrate the impact of left atrial functions which were evaluated by three different echocardiographic modalities , on postoperative atrial fibrillation.

Detailed Description

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Postoperative atrial fibrillation after coronary artery bypass greft operation (CABG) is major complication with a prevalence of 10-50%. Although the men mechanism is not known, in recent studies, age and left atrial function have been demonstrated as the most responsible factors. Velocity vector imaging (VVI) is a new modality which may give accurate and detailed information on both left atrial segmental and global function. In this study, our aim was to assess preoperative left atrial function by using three different echocardiographic modalities, VVI, tissue Doppler imaging and conventional echocardiography and evaluate the relation between the left atrial functions and the development of post-operative atrial fibrillation after CABG.

Conditions

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Atrial Fibrillation

Keywords

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atrial fibrillation, left atrium, velocity vector imaging

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Patients with postoperative atrial fibrillation

No interventions assigned to this group

2

Patients without postoperative atrial fibrillation.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 1Coronary artery disease evidenced by coronary angiography
* 2Patients with a decision of undergoing elective coronary artery bypass greft operation
* 3Sinus rhythm in electrocardiography

Exclusion Criteria

* 1Rheumatic valve disease
* 2Having prosthetic valve
* 3CABG accompanied by other cardiac interventions (such as valvular surgery, ASD closure...etc)
* 4Left ventricular l ejection fraction \<40%
* 5Mild to moderate mitral stenosis or regurgitation
* 6Having atrial fibrillation or a history of atrial fibrillation attach during the last two weeks.
* 7Congenital heart disease
* 8Chronic liver disease
* 9Chronic renal disease
* 10Malignancy

Minimum Eligible Age

30 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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T.C. Istanbul Bilim University, Florence Nightingale Hospital

Principal Investigators

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Saide Aytekin, Professor

Role: STUDY_DIRECTOR

T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology

Locations

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TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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1-Leung JM, Bellows WH, Schiller NB. Impairment of left atrial function predicts post-operative atrial fibrillation after coronary artery bypass graft surgery. European H J. 2004,25,1836-1844 2-Nakai T , Lee R, Schiller N, et al. The relative importance of left atrial function versus dimension in predicting atrial fibrilation after coronary bypass graft surgery. Am H Journal. 2002; 143:181-6

Reference Type BACKGROUND

Other Identifiers

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YT1977/2

Identifier Type: -

Identifier Source: org_study_id