Transoesophageal Echocardiography in Liver Transplantation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

17 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-04-30

Study Completion Date

2010-01-31

Brief Summary

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Severe hypotension during reperfusion in liver transplantation is a frequent adverse event. Rare data exist so far about pathophysiology of this phenomenon. The exact role of left ventricular function, which might be impaired causing hypotension, has not been elucidated during the period of reperfusion.

Goal of this study is to:

* perform transesophageal echocardiography in order to assess systolic and diastolic left ventricular function during reperfusion
* determine inflammatory mediators in the plasma which could cause left ventricular dysfunction

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Detailed Description

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Conditions

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End Stage Liver Disease

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Transoesophageal echocardiography

Transoesophageal echocardiography in liver transplantation: left ventricular function during reperfusion

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients on waiting list for liver transplantation.
* Age: 18-75 years.

Exclusion Criteria

* Strictures, tumours and diverticula of the oesophagus.
* History of oesophageal varices with recent bleeding.
* Oesophageal varices and prothrombin time less than 20% or platetlets les than 30000/ml.
* Instable cervical spine.
* Involvement in other studies.

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No