Clinical Research to Explore Manifestations of Heart Failure Using Infrared Thermal Imaging Technology

NCT ID: NCT02672618

Last Updated: 2016-02-03

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 200 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2015-11-30
• Study Completion Date: 2017-06-30

Brief Summary

The purpose of this study is to explore manifestations of Heart Failure Using Infrared Thermal Imaging Technology.

Detailed Description

Temperature is a vital and useful indicator for various diseases.Infrared thermal imaging (IRTI) allows the temperature representation of the body surface by thermal distribution, where it depends on the complex relationships defining the heat exchange processes between skin tissue, inner tissue, local vasculature, and metabolic activity.

The decrease in cardiac output in heart failure activate a series of compensatory adaption that are intended to maintain cardiovascular homeostasis. One of most important adaptation is activation of sympathetic nervous system, which could cause peripheral cutaneous vasoconstriction and decrease the skim temperature. Hence, the skim temperature of heart failure would be lower than health people,but which could not discovery by eye. The investigators hypothesize that IRTI could evaluate heart failure by the imaging of temperature distribution in the face on early stages.The aim of this study is to determine the effectiveness of infrared thermal imaging in evaluating heart failure.

Conditions

Heart Failure，Congestive

Study Design

• Study Time Perspective: CROSS_SECTIONAL

Study Groups

chronic heart failure

18-85years old,having symptoms of heart failure,New York Heart Association（NYHA） class II or above American College of Cardiology/American Heart Association（ACC/AHA） class B, C, including hypertensive heart disease, rheumatic heart disease, ischemic cardiomyopathy and idiopathic cardiomyopathy

Intervention Type: OTHER

The IRS system is capable of precisely measuring and storing real-time thermal images with a resolution of 320×240 pixels (IRS S6md Shanghai,China). The camera has Focal Plane Array (FPA), Uncooled microbolometer detector, with a thermal sensitivity of 0.05 ℃ at 20℃ to 30℃. The thermal images were captured at a distance of one meter from the various body regions namely face and the images were analyzed by thermal software（version 1.0）.

normalCardiac function

18-85years old,no symptoms of heart failure,NYHA class I or above ACC/AHA class A, including controled hypertension,stability coronary heart disease and rheumatic heart disease

Intervention Type: OTHER

The IRS system is capable of precisely measuring and storing real-time thermal images with a resolution of 320×240 pixels (IRS S6md Shanghai,China). The camera has Focal Plane Array (FPA), Uncooled microbolometer detector, with a thermal sensitivity of 0.05 ℃ at 20℃ to 30℃. The thermal images were captured at a distance of one meter from the various body regions namely face and the images were analyzed by thermal software（version 1.0）.

healthy volunteers

18-85years old,Without basic cardiovascular diseases

Intervention Type: OTHER

The IRS system is capable of precisely measuring and storing real-time thermal images with a resolution of 320×240 pixels (IRS S6md Shanghai,China). The camera has Focal Plane Array (FPA), Uncooled microbolometer detector, with a thermal sensitivity of 0.05 ℃ at 20℃ to 30℃. The thermal images were captured at a distance of one meter from the various body regions namely face and the images were analyzed by thermal software（version 1.0）.

Interventions

The IRS system is capable of precisely measuring and storing real-time thermal images with a resolution of 320×240 pixels (IRS S6md Shanghai,China). The camera has Focal Plane Array (FPA), Uncooled microbolometer detector, with a thermal sensitivity of 0.05 ℃ at 20℃ to 30℃. The thermal images were captured at a distance of one meter from the various body regions namely face and the images were analyzed by thermal software（version 1.0）.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1. Willing to participate in the trial and sign the informed consent form

2. Aged: 18-85 years

3. Was diagnosed as heart failure

4. There is no trauma, infection, biopsy or puncture, hemorrhage and tumor in the corresponding detection site (face)

5. There is no skin disease, heart, liver, kidney, gastrointestinal tract, hematopoietic system and mental, neurological has no serious diseases

Exclusion Criteria

1. Fever causes by any reasons, temperature higher than 37.4℃

2. Infection

3. Renal failure

4. Cerebrovascular diseases

5. Moderate anemia or more

6. Not willing to participate in clinical trials

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Jing Huang

OTHER

Sponsor Role: lead

Responsible Party

Jing Huang

professor，vice director

Responsibility Role: SPONSOR_INVESTIGATOR

Principal Investigators

hang jing

Role: STUDY_DIRECTOR

Chongqing Medical University

Locations

The 2nd Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Site Status: RECRUITING

3Rd People'S Hospital of Chengdu

Chengdu, Sichuan, China

Site Status: NOT_YET_RECRUITING

The First Affiliated Hospital of Sichuan Medical University:

Luzhou, Sichuan, China

Site Status: NOT_YET_RECRUITING

The First Affiliated Hospital of Chongqing Medical University:

Chongqing, , China

Site Status: NOT_YET_RECRUITING

Countries

China

Central Contacts

huang jing

Role: CONTACT

huangjing@cqmu.edu.cn

Facility Contacts

Jing Huang, MD

Role: primary

huangjing@cqmu.edu.cn

0086-13508312022

Wang chunbin

Role: primary

Jiang feng

Role: primary

Guo rui

Role: primary

Other Identifiers

JHuang

Identifier Type: -

Identifier Source: org_study_id