The Effect of Phosphorus on Diet Induced Thermogenesis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

23 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Study Completion Date

2014-01-31

Brief Summary

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The aim of the trial is to investigate the effect of ingestion of 75g of glucose (with or without phosphorus) on diet induced thermogenesis (using indirect calorimetry) and appetite (using visual analogue scales) in lean and obese healthy subjects

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Detailed Description

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Conditions

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Imbalance of Constituents of Food Intake Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Phosphorus

Intervention (500 mg of potassium phosphate) will be administered with 75 g glucose solution and diet induced thermogenesis will be measured afterwards

Group Type ACTIVE_COMPARATOR

Phosphorus

Intervention Type DIETARY_SUPPLEMENT

Placebo

Placebo (cellulose) will be administered with 75 g glucose solution and diet induced thermogenesis will be measured afterwards

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Interventions

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Phosphorus

Intervention Type DIETARY_SUPPLEMENT

Placebo

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy
* Sedentary lifestyle
* Stable weight for the past 3 months
* On a balanced diet

Exclusion Criteria

* Underweight (BMI\<18.5) or overweight/obese (BMI≥25)
* age \<18 or \> 30 years
* Inability to give valid consent
* Presence of a chronic or acute illness.
* Elevated physical activity level (assesses by the physical activity questionnaire)
* Heavy smokers (≥1 pack per day).
* Weight gain or loss of \> 3% in the past 3 months
* History of kidney stones

Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes