ED Lung Protective Ventilation to Reduce Complications

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1705 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-10-31

Study Completion Date

2016-03-31

Brief Summary

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Early mechanical ventilation, if delivered with injurious settings, can lead to pulmonary complications, such as acute respiratory distress syndrome (ARDS). Mechanical ventilation in the emergency department (ED) has been studied infrequently when compared to the intensive care unit; however, data suggests that ED-based mechanical ventilation has significant room for improvement and may also be a causative factor in ARDS incidence.

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Detailed Description

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This is a before-after study examining the impact of implementing lung protective ventilation in the emergency department.

Conditions

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Mechanical Ventilation Ventilator-associated Conditions ARDS

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Study Groups

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Pre-intervention group

mechanically ventilated patients before implementation of ED lung protective ventilation

No interventions assigned to this group

Intervention group

mechanically ventilated patients after implementation of ED lung protective ventilation

lung protective ventilation

Intervention Type PROCEDURE

Lung protective ventilation strategy, which aims to deliver safe tidal volumes, appropriate PEEP, limit plateau pressure, and limit hyperoxia.

Interventions

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lung protective ventilation

Lung protective ventilation strategy, which aims to deliver safe tidal volumes, appropriate PEEP, limit plateau pressure, and limit hyperoxia.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* mechanically ventilated via an endotracheal tube in the ED

Exclusion Criteria

* death in the ED,
* death or discontinuation of ventilation within 24 hours,
* chronic mechanical ventilation,
* ARDS while in the ED
* transfer to another hospital.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No