Clinical Outcomes of the Freedom Spinal Cord Stimulation (SCS) System for the Management of Chronic Back and Leg Pain

NCT ID: NCT02403518

Last Updated: 2020-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-10-31

Study Completion Date

2020-09-30

Brief Summary

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This study evaluates the Freedom SCS (spinal cord stimulation) System for the treatment of chronic back and leg pain. Patients who have been diagnosed with failed back surgery syndrome (FBSS) will receive a stimulator device for treatment of their pain.

Detailed Description

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Conditions

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Chronic Low Back Pain Pain in Leg, Unspecified

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Back Pain Only

Pain localized to the low back or buttocks.

Group Type ACTIVE_COMPARATOR

Freedom Spinal Cord Stimulator System

Intervention Type DEVICE

Leg Pain Only

Pain localized to unilateral pain of the leg (thigh, knee, calf, or foot).

Group Type ACTIVE_COMPARATOR

Freedom Spinal Cord Stimulator System

Intervention Type DEVICE

Back and Leg Pain

Pain localized to both the low back and legs (back, buttocks, thigh, knee, calf, or foot).

Group Type ACTIVE_COMPARATOR

Freedom Spinal Cord Stimulator System

Intervention Type DEVICE

Interventions

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Freedom Spinal Cord Stimulator System

Intervention Type DEVICE

Other Intervention Names

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Freedom-4 SCS System Freedom-4A SCS System Freedom-8A SCS System

Eligibility Criteria

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Inclusion Criteria

* Appropriate Freedom SCS candidate as affirmed by study investigator
* Candidate has a stable spine not suitable for further surgery as confirmed by physician
* 18 years of age or older (no upper age limit)
* Diagnosis of failed back surgery syndrome (FBSS) characterized by chronic, intractable pain of the legs, back, or both legs and back
* At least 6 months since last surgical procedure on the spine
* Average score of 60mm or greater on a VAS scale (Scale of 0 to 100, where 0 equals no pain and 100 equals worst possible pain)
* Pain duration of at least 6 months
* Expected lifespan of at least two years
* Able to comply with study requirements
* Gives informed consent for study participation

Exclusion Criteria

* A consistent VAS score of 100 over the past 24 hours as established at Visit 1
* A co-existing condition that could increase the risk of SCS implantation (e.g., severe cardiac or respiratory disorders, coagulation disorder) or planned surgery within the study duration that could be compromised by SCS (e.g., diathermy)
* Pregnant or planning to become pregnant
* Known or suspected substance abuse within the last 2 years
* Major psychiatric disorder (untreated or refractory to treatment) in the investigators opinion
* Cognitive and/or behavioral issues that could impair study participation, (e.g., unreliability; defective memory; noncompliance in taking medications or keeping appointments; or impaired orientation to time, place, and events)
* Documented allergy to Freedom SCS material components
* Co-existing pain condition or participation in another clinical study that could confound the results of this study
* History of another implanted medical device (e.g., explanted spinal cord stimulator, peripheral nerve stimulation, sacral nerve stimulator, pacemaker, or intrathecal drug delivery)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Amphia ziekenhuis, Oosterhout, The Netherlands

UNKNOWN

Sponsor Role collaborator

Curonix LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Greg Jansen

Role: PRINCIPAL_INVESTIGATOR

Amphia ziekenhuis Oosterhout

Locations

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Amphia Ziekenhuis

Oosterhout, North Brabant, Netherlands

Site Status

Countries

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Netherlands

Other Identifiers

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05-0071

Identifier Type: -

Identifier Source: org_study_id

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