Return to Work for Persistent Spinal Pain Syndrome Type II Patients

NCT ID: NCT05269212

Last Updated: 2025-10-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

112 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-10

Study Completion Date

2027-08-31

Brief Summary

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A multicenter randomized controlled trial will be conducted to evaluate whether the ability to work in Persistent Spinal Pain Syndrome Type II (PSPS-T2) patients after SCS implantation is different after a personalized biopsychosocial rehabilitation program specifically targeting return to work (RTW) compared with usual care.

Detailed Description

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A multicenter randomized controlled trial will be conducted to evaluate whether the ability to work in Persistent Spinal Pain Syndrome Type II patients after SCS implantation is different after a personalized biopsychosocial rehabilitation program specifically targeting return to work compared with usual care.

The primary scientific objective is to examine whether the ability to work in PSPS-T2 patients after SCS implantation is different with a personalized biopsychosocial rehabilitation program specifically targeting RTW, compared to usual care. The secondary objective of the study is to examine if a personalized biopsychosocial rehabilitation program specifically targeting RTW, compared to usual care, is different in improving functional capacity, improving work status and participation, obtaining pain relief, increasing health-related quality of life, increasing functioning and physical activity, improving sleep quality, decreasing kinesiophobia, increasing self-management, decreasing anxiety and depression and decreasing healthcare expenditure.

Patients will be randomly allocated (1:1 ratio) to a personalized rehabilitation program or usual care using random, permuted blocks of 2 or 4 patients stratified by investigational site and the duration of sick leave. Participants randomly allocated to the usual care intervention will undergo the usual care trajectory. This program is delivered at each of the participating centres. Patients will follow the usual care as it is implemented in Belgian hospitals, after SCS implantation. Participants randomly allocated to the personalized biopsychosocial return to work program will receive an individualized 14-week rehabilitation program. Therapy is provided at each implantation centres and will start 6 weeks after definitive SCS implantation. Within a 14-week period, patients in this group receive treatment sessions from trained physiotherapists, occupational therapists and psychologists. All therapists will be trained by experts in the different therapy modalities.

Outcome assessments will take place at baseline, immediately before the intervention, immediately after the intervention, 3 months after the intervention, 6 months after the intervention and 12 months after the intervention.

Conditions

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Failed Back Surgery Syndrome Spinal Cord Stimulation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors

Study Groups

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Usual care

Group Type ACTIVE_COMPARATOR

Usual Care trajectory

Intervention Type OTHER

Usual care after Spinal Cord Stimulation implantation

Personalized biopsychosocial rehabilitation program

Group Type ACTIVE_COMPARATOR

A biopsychosocial rehabilitation program

Intervention Type OTHER

A personalized biopsychosocial rehabilitation program specifically targeting return to work.

Interventions

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Usual Care trajectory

Usual care after Spinal Cord Stimulation implantation

Intervention Type OTHER

A biopsychosocial rehabilitation program

A personalized biopsychosocial rehabilitation program specifically targeting return to work.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Persistent Spinal Pain Syndrome Type II (PSPS-T2)
* Chronic pain as a result of PSPS-T2 that exists for at least 6 months with a pain intensity of at least 4/10 on the Numeric Rating Scale, refractory to conservative treatment.
* Dutch speaking persons
* Patient has been informed of the study procedures and has given written informed consent
* Patient willing to comply with study protocol including attending the study visits

Exclusion Criteria

* Suffering from another chronic illness characterised by chronic generalized widespread pain (e.g. rheumatoid arthritis, fibromyalgia, chronic fatigue syndrome, scleroderma).
* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vrije Universiteit Brussel

OTHER

Sponsor Role collaborator

University Ghent

OTHER

Sponsor Role collaborator

KU Leuven

OTHER

Sponsor Role collaborator

Moens Maarten

OTHER

Sponsor Role lead

Responsible Party

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Moens Maarten

principal investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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UZ Gent

Ghent, , Belgium

Site Status RECRUITING

Jessa Ziekenhuis

Hasselt, , Belgium

Site Status RECRUITING

Universitair Ziekenhuis Brussel

Jette, , Belgium

Site Status RECRUITING

AZ Nikolaas

Sint-Niklaas, , Belgium

Site Status NOT_YET_RECRUITING

AZ Turnhout

Turnhout, , Belgium

Site Status NOT_YET_RECRUITING

Countries

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Belgium

Central Contacts

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Maarten Moens, Prof. dr.

Role: CONTACT

+3224775514

Lisa Goudman, PhD

Role: CONTACT

Facility Contacts

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Sam Schelfout, MD

Role: primary

Mark Plazier, MD PhD

Role: primary

Maarten Moens, MD PhD

Role: primary

Jean-Pierre Van Buyten, MD PhD

Role: primary

Bart Bryon, MD

Role: primary

References

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Moens M, Goudman L, Van de Velde D, Godderis L, Putman K, Callens J, Lavreysen O, Ceulemans D, Leysen L; OPERA consortium; De Smedt A. Personalised rehabilitation to improve return to work in patients with persistent spinal pain syndrome type II after spinal cord stimulation implantation: a study protocol for a 12-month randomised controlled trial-the OPERA study. Trials. 2022 Dec 5;23(1):974. doi: 10.1186/s13063-022-06895-5.

Reference Type DERIVED
PMID: 36471349 (View on PubMed)

Other Identifiers

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OPERA

Identifier Type: -

Identifier Source: org_study_id

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