To Examine Whether or Not the Primary Causes of OA or RA Might be Bone Alterations

NCT ID: NCT02327650

Last Updated: 2021-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-11-30

Study Completion Date

2024-12-31

Brief Summary

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Generally, osteoarthris (OA) is considered as primarily cartilage disease. However, as we and others have previously reported, a portion of OA might be caused primarily by bone alterations. In this study, we prospectively and retrospectively show that the bone altertations may affect OA primarily in all of the joints.

In addition, rheumatoid arthritis (RA) is a joint disease when immune system attacks synovium. Joint destruction occurrs continuously if suitable treatment is not performed. The etiology of RA is still largely unknown. As with OA, RA can be primarily damaged in bone, instead of cartilage. Here we prospectively and retrospectively show that the bone altertations may affect RA primarily in all of the joints.

Detailed Description

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Conditions

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Progression of Rheumatoid Arthritis Osteoarthritis of Multiple Joints

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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RA and OA

Every 2 or 3 months, plain radiograph, blood and urinary tests, and MRI are performed in the painful joints of RA.

The examinations for bones in joints of OA and RA patients

Intervention Type PROCEDURE

Interventions

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The examinations for bones in joints of OA and RA patients

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* RA and/or OA

Exclusion Criteria

* N/A
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Shinshu University

OTHER

Sponsor Role lead

Responsible Party

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Yukio Nakamura

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Yukio Nakamura

Matsumoto, Nagano, Japan

Site Status RECRUITING

Yukio Nakamura

Matsumoto, , Japan

Site Status RECRUITING

Countries

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Japan

Facility Contacts

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Yukio Nakamura, MD, PhD

Role: primary

+81-263-37-2659

Yukio Nakamura

Role: primary

Other Identifiers

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OA RA Bone Study

Identifier Type: -

Identifier Source: org_study_id

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