Enthesis Differences in Rheumatoid Arthritis and Axial Spondyloarthropathy

NCT ID: NCT05942976

Last Updated: 2023-09-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

106 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-16

Study Completion Date

2023-08-15

Brief Summary

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The aim of this study is to investigate the sonographic differences in entheses in patients with Rheumatoid arthritis and Axial Spondyloarthropathy.

Detailed Description

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After recording the demographic data of the patients; 5 enthesis regions 5 enthesis sites were evaluated bilaterally as ''tricipital tendon (TT), quadricipital tendon (QT), proximal patellar tendon (PPT), distal patellar tendon (DPT), achilles tendon (AT)'' will be sonographically evaluated and the presence of hypoechogenicity , tendon thickness increase, power Doppler activity, erosion, presence of entezophyte/calcification will be investigated. The differences between the groups will then be compared.

Conditions

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Axial Spondyloarthritis Rheumatoid Arthritis Enthesitis Enthesopathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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group 1: axial spondyloarthritis

SpA patients identified according to the Assessment of Spondyloarthritis classification criteria

ULTRASOUND

Intervention Type OTHER

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

group 2: Rheumatoid arthritis

RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria

ULTRASOUND

Intervention Type OTHER

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

group:3 Healthy Control

healthy controls with no history of rheumatic diseases

ULTRASOUND

Intervention Type OTHER

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

Interventions

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ULTRASOUND

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Rheumatoid arthritis patients identified according to the 2010 American College of Rheumatology /Europan Leage Against Rheumatism classification criteria,
* axial Spondyloarthrtis patients identified according to the Assessment of Spondyloarthritis classification criteria
* healthy controls with no history of rheumatic diseases.

Exclusion Criteria

* history of limb trauma and surgery in the last 3 months,
* metabolic disease (diabetes mellitus, hypothyroidism),
* malignant neoplasm,
* limitation of range of motion in the extremity,
* those who have received corticosteroid injections in the last 3 months,
* uncontrollable fibromyalgia.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Istanbul Training and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Burak Tayyip Dede

Medical Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Istanbul Training and Resarch Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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16/09/2022; 2011-KAEK-50;288

Identifier Type: -

Identifier Source: org_study_id

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