The Effects on Growth and Tolerance of an Infant Formula Fed to Term Infants

NCT ID: NCT01897922

Last Updated: 2015-09-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

348 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-07-31

Study Completion Date

2014-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This clinical trial will evaluate an investigational infant formula with a probiotic to determine if it provides normal growth and if it is well tolerated by term infants compared to a marketed routine infant formula.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Growth of Term Infants

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

DOUBLE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Marketed routine infant formula

Group Type ACTIVE_COMPARATOR

Control: Marketed routine infant formula

Intervention Type OTHER

Infant formula containing a probiotic source

Group Type EXPERIMENTAL

An investigational infant formula containing a probiotic source

Intervention Type OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

An investigational infant formula containing a probiotic source

Intervention Type OTHER

Control: Marketed routine infant formula

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Singleton, 12-16 days of age at randomization
* Term infant with birth weight of a minimum of 2500 grams
* Solely formula fed
* Signed Informed Consent and Protected Health Information

Exclusion Criteria

* History of underlying metabolic or chronic disease or immunocompromised
* Feeding difficulties or formula intolerance
Minimum Eligible Age

12 Days

Maximum Eligible Age

16 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Mead Johnson Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Carol Lynn Berseth, M.D.

Role: STUDY_DIRECTOR

Mead Johnson Nutrition

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Birmingham Pediatric Associates

Birmingham, Alabama, United States

Site Status

Greenvale Pediatrics Hoover

Birmingham, Alabama, United States

Site Status

Southeastern Pediatric Associates

Dothan, Alabama, United States

Site Status

Pediatrics East - Alabama Clinical Therapeutics

Pinson, Alabama, United States

Site Status

The Children's Clinic of Jonesboro, P.A.

Jonesboro, Arkansas, United States

Site Status

Arkkansas Pediatric Clinic

Little Rock, Arkansas, United States

Site Status

Norwich Pediatric Group, P.C.

Norwich, Connecticut, United States

Site Status

Children's Research, LLC

Altamonte Springs, Florida, United States

Site Status

Children's Medical Associations

Plantation, Florida, United States

Site Status

Deaconess Clinical Research

Evansville, Indiana, United States

Site Status

Owensboro Pediatrics

Owensboro, Kentucky, United States

Site Status

Woburn Pediatic Associates

Woburn, Massachusetts, United States

Site Status

Cary Pediatric Center, P.A.

Cary, North Carolina, United States

Site Status

Capital Pediatrics & Adolescent Center

Raleigh, North Carolina, United States

Site Status

Pediatric Associates of Mt. Carmel, Inc

Cincinnati, Ohio, United States

Site Status

Pediatric Associates of Fairfield, Inc.

Fairfield, Ohio, United States

Site Status

Parma Pediatrics, Inc

Parma, Ohio, United States

Site Status

UHMP Comprehensive Pediatrics

Westlake, Ohio, United States

Site Status

The Jackson Clinic - North Jackson

Jackson, Tennessee, United States

Site Status

Holston Medical Group

Kingsport, Tennessee, United States

Site Status

Austin Diagnostic Clinic

Austin, Texas, United States

Site Status

DCOL Center for Clinical Research

Longview, Texas, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

References

Explore related publications, articles, or registry entries linked to this study.

Berseth CL, Yeiser M, Harris CL, Kinnaman JN, Lappin V, Wampler JL, Zhuang W, Vanderhoof J. Infant formula with added Lacticaseibacillus rhamnosus GG supported adequate growth and was well tolerated in healthy term infants: a randomized controlled trial. Front Pediatr. 2024 Oct 23;12:1456607. doi: 10.3389/fped.2024.1456607. eCollection 2024.

Reference Type DERIVED
PMID: 39507493 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

3385-2

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Starter Infant Formula With Synbiotics
NCT06073652 ACTIVE_NOT_RECRUITING NA