Efficacy of a New Infant Formula Composition on Gut Health in Infants

NCT ID: NCT07242508

Last Updated: 2025-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-25

Study Completion Date

2026-08-19

Brief Summary

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The aim of this study is to investigate potential health benefits of the experimental formula. The main objective is whether the experimental formula elevates the relative abundance of Bifidobacterium in stool samples after 10 weeks, as compared a standard formula, aka control formula. In addition other markers of gut health, such as stool characteristics, and gut health symptoms will be monitored

Detailed Description

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Conditions

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Healthy Infants

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Experimental infant formula

Infant formula with bioactive ingredients

Group Type EXPERIMENTAL

Infant Formula with bioactive ingredients

Intervention Type OTHER

ad-libitum consumption

Control formula

Standard infant formula

Group Type PLACEBO_COMPARATOR

Infant Formula

Intervention Type OTHER

ad-libitum consumption of infant formula

Interventions

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Infant Formula

ad-libitum consumption of infant formula

Intervention Type OTHER

Infant Formula with bioactive ingredients

ad-libitum consumption

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy, full term, infants with a birth weight between 2500-4500 grams
* Parents independently from study decided to not breastfeed their infant
* Parents agree to feed the assigned study formula as the infant's sole source of nutrition for the duration of the study
* have read and voluntarily signed an informed consent form
* parents are capable of completing study procedures required by the protocol

Exclusion Criteria

* suffering from any anatomic and/or physiologic condition that would interfere with normal growth, development or feeding
* are required to take medications or supplements known to influence growth and development
* have a maternal history with known adverse effects on the fetus and/or the newborn infant
* have previous or current antibiotics use (antibiotics administered during delivery are permitted)
* have received or are planning to receive probiotics, prebiotics, or nutritional supplements prior to and throughout the trial (excluding vitamin D and vitamin K supplementation)
* personal history of or parents/siblings diagnosed with cow's milk protein allergy or lactose intolerance
* multiple birth
* participation in another trial
Minimum Eligible Age

0 Days

Maximum Eligible Age

3 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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FrieslandCampina

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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ECCT2831

Identifier Type: -

Identifier Source: org_study_id

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