Tolerance of Healthy Term Infants Fed Infant Formulas #4

NCT ID: NCT01155414

Last Updated: 2011-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

168 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-03-31

Study Completion Date

2010-07-31

Brief Summary

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The primary objective of this study is to assess the comparative gastrointestinal (GI) tolerance of normal term infants to two experimental powdered formulas compared with a commercially available powdered formula.

Detailed Description

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Conditions

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Healthy Term Infants

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Investigational infant formula A

Investigational Protein Hydrolysate formula

Group Type EXPERIMENTAL

Investigational Infant Formula A

Intervention Type OTHER

Investigational infant formula ad lib

Hydrolysate based Infant Formula

Group Type ACTIVE_COMPARATOR

Hydrolysate based infant formula

Intervention Type OTHER

Infant formula ad lib

Investigational Infant Formula B

Investigational Protein Hydrolysate Formula

Group Type EXPERIMENTAL

Investigational Infant Formula B

Intervention Type OTHER

Investigational infant formula ad lib

Interventions

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Hydrolysate based infant formula

Infant formula ad lib

Intervention Type OTHER

Investigational Infant Formula A

Investigational infant formula ad lib

Intervention Type OTHER

Investigational Infant Formula B

Investigational infant formula ad lib

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Singleton full term birth in good health
* Birth weight was \> 2490 g.
* Between 0 and 8 days of age.
* Infants using medications (including OTC such as Mylicon® for gas), home remedies (such as juice for constipation), herbal preparations or rehydration fluids that might affect GI tolerance may not be enrolled unless both the parent and the physician agree to discontinue these agents prior to enrollment.
* Parent(s) confirm their intention to feed their infant the study product as the sole source of nutrition for the duration of the study, unless instructed otherwise by their healthcare professional.
* Parent(s) confirm their intention not to administer vitamin or mineral supplements, solid foods or juices to their infant from enrollment through the duration of the study.

Exclusion Criteria

• An adverse maternal, fetal or infant medical history and treatment with antibiotics
Minimum Eligible Age

1 Day

Maximum Eligible Age

8 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Abbott Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marlene Borschel, PhD

Role: STUDY_CHAIR

Abbott Nutrition

Locations

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Alabama Clinical Therapeutics, LLC

Birmingham, Alabama, United States

Site Status

Alabama Clinical Therapeutics, LLC

Dothan, Alabama, United States

Site Status

SCORE Physician Alliance

St. Petersburg, Florida, United States

Site Status

University of Iowa

Coralville, Iowa, United States

Site Status

Medical Associates Clinic, PC

Dubuque, Iowa, United States

Site Status

MetroHealth Medical Center

Cleveland, Ohio, United States

Site Status

Ohio Pediatric Research Association

Huber Heights, Ohio, United States

Site Status

Institute of Clinical Research

Mayfield Heights, Ohio, United States

Site Status

Pediatric Clinical Research Office

Hershey, Pennsylvania, United States

Site Status

The Jackson Clinic, PA

Jackson, Tennessee, United States

Site Status

Countries

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United States

Other Identifiers

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AK75

Identifier Type: -

Identifier Source: org_study_id