Growth and Tolerance of Young Infants Fed Infant Formula

NCT ID: NCT04105686

Last Updated: 2021-01-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

366 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-09-30

Study Completion Date

2020-12-04

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is a randomized, multicenter, controlled, double-blind, parallel study to evaluate growth and tolerance of healthy term infants fed milk-based infant formulas.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Growth and Tolerance

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control Infant Formula

Milk-based study product

Group Type ACTIVE_COMPARATOR

Control Infant Formula

Intervention Type OTHER

Ready to feed infant formula, feed ad libitum

Experimental Infant Formula

Milk-based study product with oligosaccharides

Group Type EXPERIMENTAL

Experimental Infant Formula

Intervention Type OTHER

Ready to feed infant formula, feed ad libitum

Reference Group

Human milk-fed group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Control Infant Formula

Ready to feed infant formula, feed ad libitum

Intervention Type OTHER

Experimental Infant Formula

Ready to feed infant formula, feed ad libitum

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Participant is judged to be in good health as determined from participant's medical history.
* Participant is a singleton from a full-term birth with a gestational age of 37-42 weeks.
* Participant's birth weight was \> 2490 g (\~5 lbs. 8 oz.).
* Parent(s) who elect to formula-feed the participant, confirm their intention to feed their infant the study product as the sole source of feeding during the study.
* Parent(s) who elect to feed the participant human milk, confirm their intention to exclusively feed human milk as the sole source of feeding during the study.
* Parent(s) of formula-fed infants confirm their intention not to administer vitamin or mineral supplements, (except for vitamin D supplements), solid foods or juices to their infant from enrollment through the duration of the study.
* Parent(s) of human milk-fed infants confirm their intention not to administer solid foods or juices to their infant from enrollment through the duration of the study (vitamins and minerals are acceptable).
* Participant's parent(s) has voluntarily signed and dated an ICF, approved by an IRB/IEC and provided HIPAA (or applicable privacy regulation) authorization prior to any participation in the study.

Exclusion Criteria

* An adverse maternal, fetal or participant medical history that is thought by the investigator to have potential for effects on tolerance, growth, and/or development.
* Participant is taking and plans to continue taking medications (including over the counter), prebiotics, probiotics, home remedies, herbal preparations or rehydration fluids that might affect GI tolerance.
* Participant participates in another study that has not been approved as a concomitant study.
Maximum Eligible Age

14 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Abbott Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Timberly Williams, PhD

Role: STUDY_CHAIR

Abbott Nutrition

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Central Research Associates

Birmingham, Alabama, United States

Site Status

Southeastern Pediatric Associates

Dothan, Alabama, United States

Site Status

Visions Clinical Research

Tucson, Arizona, United States

Site Status

Applied Research Center of Arkansas

Little Rock, Arkansas, United States

Site Status

TOPAZ Clinical Research, Inc.

Apopka, Florida, United States

Site Status

University Clinical Research-Deland, LLC dba Avail Clinical Research- West Volusia Pediatrics

DeLand, Florida, United States

Site Status

Children's Research, LLC

Lake Mary, Florida, United States

Site Status

New Horizon Research Center

Miami, Florida, United States

Site Status

Pediatric & Adult Research Center

Orlando, Florida, United States

Site Status

Asclepes Research Centers

Spring Hill, Florida, United States

Site Status

Score Physician Alliance, LLC

St. Petersburg, Florida, United States

Site Status

PAS Research, LLC

Tampa, Florida, United States

Site Status

Tekton Research

Chamblee, Georgia, United States

Site Status

Saltzer Health

Nampa, Idaho, United States

Site Status

Deaconess Clinic, Inc.

Evansville, Indiana, United States

Site Status

Springs Medical Research

Owensboro, Kentucky, United States

Site Status

Meridian Clinical Research 3080

Baton Rouge, Louisiana, United States

Site Status

Meridan Clinical Research

Omaha, Nebraska, United States

Site Status

Wake Research - Clinical Research Center of Nevada

Las Vegas, Nevada, United States

Site Status

ClinOhio Research Services

Columbus, Ohio, United States

Site Status

Ohio Pediatric Research Association

Dayton, Ohio, United States

Site Status

PriMed Clinical Research

Dayton, Ohio, United States

Site Status

Institute of Clinical Research, LLC

Mentor, Ohio, United States

Site Status

The Cleveland Pediatric Research Center, LLC

Middleburg Heights, Ohio, United States

Site Status

Midsouth Center for Clinical Research

Memphis, Tennessee, United States

Site Status

Medical Research Center of Memphis

Memphis, Tennessee, United States

Site Status

Gadolin Research, LLC

Beaumont, Texas, United States

Site Status

Women's Hospital at Renaissance - Doctors Hospital at Renaissance

Edinburg, Texas, United States

Site Status

Mercury Clincial Research, Inc.

Houston, Texas, United States

Site Status

DCOL Center for Clinical Research

Longview, Texas, United States

Site Status

Aspen Clinical Research LLC

Orem, Utah, United States

Site Status

MultiCare Institute for Research and Innovation

Tacoma, Washington, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

AL31A

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Formula Tolerance of Term Infants
NCT04915937 COMPLETED NA
Preterm Infants Fed a Human Milk Fortifier
NCT05551975 NOT_YET_RECRUITING NA
Probiotic Formula and Infant Growth
NCT01476397 COMPLETED NA