Infants Fed Extensively Hydrolyzed Casein-Based Infant Formulas

NCT ID: NCT04006236

Last Updated: 2021-09-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

245 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-08-05

Study Completion Date

2021-09-20

Brief Summary

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This is a randomized, controlled, double-blind, multicenter parallel study to evaluate the growth, tolerance and compliance of healthy infants fed infant formulas with extensively hydrolyzed casein protein.

Detailed Description

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Conditions

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Infant Development

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Experimental Infant Formula

extensively hydrolyzed casein protein

Group Type EXPERIMENTAL

Experimental Infant Formula

Intervention Type OTHER

Feed Ad Libitum

Control Infant Formula

extensively hydrolyzed casein protein

Group Type ACTIVE_COMPARATOR

Control Infant Formula

Intervention Type OTHER

Feed Ad Libitum

Interventions

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Experimental Infant Formula

Feed Ad Libitum

Intervention Type OTHER

Control Infant Formula

Feed Ad Libitum

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Participant is judged to be in good health
* Participant is a singleton from a full-term birth with a gestational age of 37-42 weeks
* Participant's birth weight was \> 2490 g (\~5 lbs. 8 oz.)
* Parent(s) confirm their intention to feed their infant the study product as the sole source of nutrition for the duration of the study
* Parent(s) confirm their intention not to administer vitamins, minerals (with the exception of Vitamin D supplements), solid foods or juices to their infant from enrollment throughout the duration of the study
* Participant's parent(s) has voluntarily signed and dated an Informed Consent Form (ICF), approved by an Independent Ethics Committee/Institutional Review Board (IEC/IRB) and provided Health Insurance Portability and Accountability Act (HIPAA) (or other applicable privacy regulation) authorization

Exclusion Criteria

* An adverse maternal, fetal or participant medical history that is thought by the investigator to have potential for effects on tolerance, growth, and/or development.
* Participant is taking and plans to continue taking medications, home remedies, prebiotics, probiotics, herbal preparations or rehydration fluids that might affect gastrointestinal (GI) tolerance
* Participant participates in another study that has not been approved as a concomitant study by AN.
* Participant has an allergy or intolerance to any ingredient in the study product
* Participant has been treated with antibiotics within 1 week prior to enrollment
Minimum Eligible Age

0 Days

Maximum Eligible Age

14 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Abbott Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Carlett Ramirez

Role: STUDY_CHAIR

Abbott Nutrition

Locations

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MedPharmics, LLC

Phoenix, Arizona, United States

Site Status

Watching Over Mothers & Babies

Tucson, Arizona, United States

Site Status

Paramount Research Solutions

College Park, Georgia, United States

Site Status

Springs Medical Research

Owensboro, Kentucky, United States

Site Status

MedPharmics, LLC

Metairie, Louisiana, United States

Site Status

MedPharmics, LLC

Gulfport, Mississippi, United States

Site Status

Quality Clinical Research Inc

Omaha, Nebraska, United States

Site Status

MedPharmics, LLC

Albuquerque, New Mexico, United States

Site Status

PMG Research of Peidmont Healthcare

Statesville, North Carolina, United States

Site Status

Pediatric Associates of Fairfield, Inc.

Fairfield, Ohio, United States

Site Status

Institute of Clinical Research, LLC

Mentor, Ohio, United States

Site Status

The Cleveland Pediatric Research Center, LLC

Middleburg Heights, Ohio, United States

Site Status

Children's Hospital

Sioux Falls, South Dakota, United States

Site Status

Midsouth Center for Clinical Research

Memphis, Tennessee, United States

Site Status

Ventavia Research Group, Llc

Fort Worth, Texas, United States

Site Status

Ventavia Research Group

Houston, Texas, United States

Site Status

Ventavia Research Group, LLC

Plano, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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AL33

Identifier Type: -

Identifier Source: org_study_id

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