Growth of Infants Fed an Extensively Hydrolyzed Infant Formula

NCT ID: NCT01210391

Last Updated: 2014-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

282 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-11-30

Study Completion Date

2013-07-31

Brief Summary

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The primary objective of the clinical trial is to compare growth in infants (expressed as weight gain in g/day) consuming a new extensively hydrolyzed formula (EHF) to infants consuming a commercially available EHF.

Detailed Description

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Conditions

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Growth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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New hydrolyzed infant formula

New, extensively hydrolyzed infant formula

Group Type EXPERIMENTAL

Extensively hydrolyzed whey infant formula

Intervention Type OTHER

New hydrolyzed infant formula.

Commercially available infant formula

Commercially available, extensively hydrolyzed infant formula.

Group Type ACTIVE_COMPARATOR

Extensively hydrolyzed casein infant formula

Intervention Type OTHER

Commercially available infant formula.

Interventions

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Extensively hydrolyzed whey infant formula

New hydrolyzed infant formula.

Intervention Type OTHER

Extensively hydrolyzed casein infant formula

Commercially available infant formula.

Intervention Type OTHER

Other Intervention Names

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Baby Formula Baby Formula

Eligibility Criteria

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Inclusion Criteria

* Healthy newborn singleton infant
* Full-term (\>= 37 weeks gestation)
* Birth weight between \>= 2500 and \< =4500 g
* 14 ± 3 days of age on enrollment
* Infant's mother has elected not to breastfeed
* baby has been exclusively formula fed a minimum of 3 days prior to enrollment
* Study explained and written information provided with Parent/Caregiver
* Informed consent signed (parent/legal representative)

Exclusion Criteria

* Congenital illness or malformation affecting infant feeding and/or growth
* Suspected or known allergy to cow's milk protein
* Significant pre-natal and/or post-natal disease
* Any readmission to hospital (except for hyperbilirubinemia) prior to enrollment
* Infant has received oral or IV antibiotic therapy in the 10 days prior to enrollment
* Infant receiving prescription medication (with exception of topical antibiotics and/or treatment for thrush) or frequent use of over the counter medications except vitamin and mineral supplements
* Infant has received probiotics in the seven days prior to enrollment
* Infant currently participating in another clinical study
* Infant's family who in the Investigator's assessment cannot be expected to comply with the protocol
Minimum Eligible Age

11 Days

Maximum Eligible Age

4 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Société des Produits Nestlé (SPN)

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ricardo Sorensen, MD

Role: PRINCIPAL_INVESTIGATOR

Louisiana State University Health Sciences Center in New Orleans

Locations

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Colorado Springs Health Partners

Colorado Springs, Colorado, United States

Site Status

Pedia Research

Newburgh, Indiana, United States

Site Status

Pedia Research

Owensboro, Kentucky, United States

Site Status

ARK-LA-Tex Pediatric Research

Bossier City, Louisiana, United States

Site Status

The Clinical Trials Center

New Orleans, Louisiana, United States

Site Status

Clinical Research of Nevada

Las Vegas, Nevada, United States

Site Status

Institute of Clinical Research

Mayfield Heights, Ohio, United States

Site Status

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, United States

Site Status

Cyn3rgy Research

Gresham, Oregon, United States

Site Status

Square-1 Clinical Research

Erie, Pennsylvania, United States

Site Status

Alpha Clinical Research

Clarksville, Tennessee, United States

Site Status

Jackson Clinic

Jackson, Tennessee, United States

Site Status

Scott & White Wells Branch Clinic

Austin, Texas, United States

Site Status

Scott & White Killeen Clinic

Killeen, Texas, United States

Site Status

DCOL Center for Research

Longview, Texas, United States

Site Status

Southwest Children's Research Associates

San Antonio, Texas, United States

Site Status

Scott & White Temple

Temple, Texas, United States

Site Status

Tanner Clinic

Layton, Utah, United States

Site Status

Clinical Research Partners

Richmond, Virginia, United States

Site Status

Wenatchee Valley Medical Center

Wenatchee, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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09.43.PED

Identifier Type: -

Identifier Source: org_study_id

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