Growth and Tolerance of a Partially Hydrolyzed Infant Formula

NCT ID: NCT05047978

Last Updated: 2024-01-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

244 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-08-28

Study Completion Date

2023-11-21

Brief Summary

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The purpose of this research study is to compare the growth and tolerance of infants who consume either an infant formula with intact proteins or an infant formula with partially hydrolyzed proteins through approximately 12 months of age.

Detailed Description

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Conditions

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Growth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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A routine cow's milk-based infant formula

A routine cow's milk-based infant formula

Group Type ACTIVE_COMPARATOR

Cow's milk protein infant formula

Intervention Type OTHER

A routine cow's milk-based infant formula

A partially hydrolyzed cow's milk protein (PHP) infant formula

A partially hydrolyzed cow's milk protein (PHP) infant formula

Group Type EXPERIMENTAL

Partially hydrolyzed protein infant formula

Intervention Type OTHER

A partially hydrolyzed cow's milk protein (PHP) infant formula

Interventions

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Cow's milk protein infant formula

A routine cow's milk-based infant formula

Intervention Type OTHER

Partially hydrolyzed protein infant formula

A partially hydrolyzed cow's milk protein (PHP) infant formula

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 10 to 14 days of age at randomization
* singleton birth
* Gestational age of 37 to 42 weeks
* Birth weight of 2500 g (5lbs 8oz or more)
* Exclusively receiving infant formula for at least 24 hours prior to randomization
* Parent or legal guardian has full intention to exclusively feed study formula through 120 days of age
* Parent or legal guardian agrees not to enroll infant in another interventional clinical study while participating in this study
* Signed informed consent and authorization to use and disclose Protected Health information

Exclusion Criteria

* History of underlying metabolic or chronic disease
* Evidence of feeding difficulties or history of formula intolerance
* Weight at Visit 1 is \<98% of birth weight
* Infant was born large for gestational age from a mother who was diabetic at childbirth
* Infant is immunocompromised
Minimum Eligible Age

10 Days

Maximum Eligible Age

14 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mead Johnson Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Steven Wu, Medical Director

Role: STUDY_DIRECTOR

Mead Johnson Nutrition

Locations

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Birmingham Pediatric Associates

Birmingham, Alabama, United States

Site Status

Southeastern Pediatric Associates

Dothan, Alabama, United States

Site Status

Visions Clinical Research-Tucson

Tucson, Arizona, United States

Site Status

Northwest Arkansas Pediatric Clinic

Fayetteville, Arkansas, United States

Site Status

The Children's Clinic of Jonesboro

Jonesboro, Arkansas, United States

Site Status

PAS Research

Tampa, Florida, United States

Site Status

Rophe Adult & Pediatric Medicine

Union City, Georgia, United States

Site Status

Saltzer Health

Nampa, Idaho, United States

Site Status

Springs Medical Research

Owensboro, Kentucky, United States

Site Status

Meridian Clinical Research

Grand Island, Nebraska, United States

Site Status

The Jackson Clinic

Jackson, Tennessee, United States

Site Status

DCOL Center for Clinical Research

Longview, Texas, United States

Site Status

PAS Research

McAllen, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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3391-1

Identifier Type: -

Identifier Source: org_study_id

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