Tolerance of an Extensively Hydrolyzed Protein Infant Formula Versus a Premature Infant Formula

NCT ID: NCT01987154

Last Updated: 2016-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

61 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2016-03-31

Brief Summary

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To evaluate the use of a hypoallergenic infant formula containing an extensively hydrolyzed protein source for routine nutrition.

Detailed Description

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Conditions

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Feeding Intolerance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Marketed cow milk-based premature infant formula

Group Type ACTIVE_COMPARATOR

Marketed cow milk-based premature infant formula

Intervention Type OTHER

Marketed extensively hydrolyzed casein infant formula

Group Type EXPERIMENTAL

Marketed extensively hydrolyzed casein infant formula

Intervention Type OTHER

Interventions

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Marketed cow milk-based premature infant formula

Intervention Type OTHER

Marketed extensively hydrolyzed casein infant formula

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Premature infant 28 to 33 weeks gestational age, inclusive, at birth
* Infant has never received enteral feedings or current enteral intake is less than 30 mL/kg/day
* Birth weight is greater than or equal to 700g to 1750g
* Appropriate birth weight for gestational age
* Singleton or twin birth
* Signed Informed consent

Exclusion Criteria

* Infant's mother plans to exclusively breast feed
* 5 minute APGAR score is less than or equal to 4
* Major surgery that required general anesthesia prior to randomization
* Ventilator-dependent or requiring greater than 40% FiO2 on day of randomization
* Grade III or IV intraventricular hemorrhage diagnosed prior to randomization
* Infant is currently participating in another clinical study
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mead Johnson Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mariella Baldassarre, M.D.

Role: PRINCIPAL_INVESTIGATOR

Universita degli Studi di Bari

Locations

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Azienda Ospedaliera "Ospedale Policlinico Consorziale" di Bari

Bari, Apulia, Italy

Site Status

Countries

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Italy

Other Identifiers

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6020

Identifier Type: -

Identifier Source: org_study_id

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