Cow Milk Allergy: Evaluation of the Efficacy of a New Thickened Extensively Hydrolyzed Formula in Infants With Confirmed Cow Milk Allergy

NCT ID: NCT02351531

Last Updated: 2015-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Brief Summary

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The aim of the study is to assess the hypoallergenicity of a new thickened extensively hydrolyzed formula.

Detailed Description

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Conditions

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Cow Milk Allergy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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New Thickened Extensively Hydrolyzed formula

Group Type EXPERIMENTAL

Extensively Hydrolyzed formula

Intervention Type DIETARY_SUPPLEMENT

Interventions

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Extensively Hydrolyzed formula

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* between 1 and 12 months old
* having a cow milk allergy confirmed by a positive double-blind food challenge performed in the last 3 months,
* whose parent(s) signed the informed consent form

Exclusion Criteria

* Infants mainly or exclusively breastfed,
* Infants having a weight at inclusion \< 2500g,
* Infants who refused to drink an extensively hydrolyzed formula anytime prior to inclusion,
* Infants fed an amino acid based formula
* Infants who had an anaphylactic reaction in the past,
Minimum Eligible Age

1 Month

Maximum Eligible Age

12 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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United Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre Hospitalier Régional

Namur, , Belgium

Site Status

Necker Children's Hospital

Paris, , France

Site Status

University of Naples Federico II

Naples, , Italy

Site Status

Countries

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Belgium France Italy

References

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Dupont C, Bradatan E, Soulaines P, Nocerino R, Berni-Canani R. Tolerance and growth in children with cow's milk allergy fed a thickened extensively hydrolyzed casein-based formula. BMC Pediatr. 2016 Jul 18;16:96. doi: 10.1186/s12887-016-0637-3.

Reference Type DERIVED
PMID: 27430981 (View on PubMed)

Other Identifiers

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UP-2013-02

Identifier Type: -

Identifier Source: org_study_id