Formula for Children With Cow's Milk Allergy

NCT ID: NCT02317952

Last Updated: 2017-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-05-31

Study Completion Date

2016-12-31

Brief Summary

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The purpose of this study is to determine if a new extensively hydrolyzed formula can be consumed by children with Cow's Milk Allergy.

Detailed Description

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Conditions

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Milk Allergy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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New Extensively Hydrolyzed Formula

Administered in context of oral food challenge and then for 16 weeks.

Group Type EXPERIMENTAL

Experimental Extensively Hydrolyzed Formula

Intervention Type OTHER

Comparator Formula

Administered in context of oral food challenge and then for 16 weeks.

Group Type ACTIVE_COMPARATOR

Active Comparator Formula

Intervention Type OTHER

Interventions

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Experimental Extensively Hydrolyzed Formula

Intervention Type OTHER

Active Comparator Formula

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Good health
* Parent/guardian must be willing to provide informed consent
* Parent/guardian agrees to feed study formula provided
* Confirmation of Cow's Milk Allergy

Exclusion Criteria

* No clinically significant abnormal findings on medical history, laboratory results, and physical exam.
* No medications that may interfere with or impact evaluation of the study assessments
* Allergy to extensively hydrolyzed casein formula
* Tolerance of 200 ml of cow's milk, cow's milk-based formula or food products containing intact cow's milk protein within 2 weeks of the Screening Visit
* Participation in another clinical trial within 30 days of screening where they are are receiving an active intervention
Maximum Eligible Age

13 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Perrigo Nutritionals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Cindy M Barber, PhD

Role: STUDY_DIRECTOR

Perrigo Nutritionals

Locations

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Carolina Ear Nose and Throat Clinic

Orangeburg, South Carolina, United States

Site Status

Clinical Research Center of Alabama

Birmingham, Alabama, United States

Site Status

Arkansas Children's Hosptial

Little Rock, Arkansas, United States

Site Status

Pediatric Care Medical Group

Huntington Beach, California, United States

Site Status

Children's Hospital of Los Angeles

Los Angeles, California, United States

Site Status

Choc Psf, Amc

Orange, California, United States

Site Status

Allergy Medical Group of the North Area, INC

Roseville, California, United States

Site Status

Allergy & Asthma Medical Group and Research Center, APC

San Diego, California, United States

Site Status

1st Allergy and Clinical Research Group, INC, d/b/a IMMUNOe International Research Centers

Centennial, Colorado, United States

Site Status

Sneeze Wheeze and Itch Associates

Normal, Illinois, United States

Site Status

Institute for Allergy and Asthma

Chevy Chase, Maryland, United States

Site Status

Einstein Consulting Services, LLC & Virgo Carter Pediatrics

Silver Spring, Maryland, United States

Site Status

Clinical Research Institute

Plymouth, Minnesota, United States

Site Status

Clinical Research Solutions, LLC

Middleburg Heights, Ohio, United States

Site Status

Allergy, Asthma, and Clinical Research Center

Oklahoma City, Oklahoma, United States

Site Status

TTS Research

Boerne, Texas, United States

Site Status

STAAMP Clinical Research

San Antonio, Texas, United States

Site Status

Seattle Children's Hospital

Seattle, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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PRG-VA-14-001

Identifier Type: -

Identifier Source: org_study_id

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