Growth and Tolerance of Hypoallergenic Formulas

NCT ID: NCT01354366

Last Updated: 2013-08-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

511 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-07-31

Study Completion Date

2012-12-31

Brief Summary

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This clinical trial will evaluate two investigational hypoallergenic infant formulas with a differing protein content to determine if they provide normal growth and are well tolerated by term infants as compared to a marketed hypoallergenic formula.

Detailed Description

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Conditions

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Growth of Term Infants

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Control

Marketed hypoallergenic infant formula containing a probiotic

Infant formula

Intervention Type OTHER

Experimental 1

An investigational hypoallergenic infant formula with a different protein content, containing the same probiotic as the control

Infant formula

Intervention Type OTHER

Experimental 2

An investigational hypoallergenic infant formula with a different protein content, without a probiotic

Infant formula

Intervention Type OTHER

Interventions

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Infant formula

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Singleton, 12-16 days of age at randomization
* Term infant with birth weight of a minimum of 2500 grams
* Solely formula fed
* Signed Informed Consent and Protected Health Information

Exclusion Criteria

* History of underlying metabolic or chronic disease or immunocompromised
* Feeding difficulties or formula intolerance
Minimum Eligible Age

12 Days

Maximum Eligible Age

16 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mead Johnson Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Mead Johnson Nutrition

Principal Investigators

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Timothy Cooper, M.D.

Role: STUDY_DIRECTOR

Mead Johnson Nutrition

Locations

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Birmingham Pediatric Associates

Birmingham, Alabama, United States

Site Status

Southeastern Pediatric Associates

Dothan, Alabama, United States

Site Status

Pediatrics East - Alabama Clinical Therapeutics

Pinson, Alabama, United States

Site Status

Central Arkansas Pediatric Clinic

Benton, Arkansas, United States

Site Status

The Children's Clinic of Jonesboro

Jonesboro, Arkansas, United States

Site Status

Arkansas Pediatric Clinic

Little Rock, Arkansas, United States

Site Status

Norwich Pediatric Group, P.C.

Norwich, Connecticut, United States

Site Status

Altamonte Pediatric Associates

Lake Mary, Florida, United States

Site Status

Children's Medical Association

Plantation, Florida, United States

Site Status

North Georgia Clinical Research Center/White's Pediatrics

Dalton, Georgia, United States

Site Status

Deaconess Clinic

Newburgh, Indiana, United States

Site Status

PTCU/Children and Youth Project

Louisville, Kentucky, United States

Site Status

Owensboro Pediatrics

Owensboro, Kentucky, United States

Site Status

Woburn Pediatric Associates

Woburn, Massachusetts, United States

Site Status

Gretchen Swanson Center for Nutrition

Omaha, Nebraska, United States

Site Status

Capital Pediatrics & Adolescent Center

Raleigh, North Carolina, United States

Site Status

Innovis Health South University

Fargo, North Dakota, United States

Site Status

Pediatric Associates of Mt. Carmel, Inc

Cincinnati, Ohio, United States

Site Status

Pediatric Associates of Fairfield, Inc

Fairfield, Ohio, United States

Site Status

Red Lion Pediatrics

Philadelphia, Pennsylvania, United States

Site Status

Primary Physicians Research, Inc

Pittsburgh, Pennsylvania, United States

Site Status

The Jackson Clinic - North Jackson

Jackson, Tennessee, United States

Site Status

Holston Medical Group

Kingsport, Tennessee, United States

Site Status

Austin Diagnostic Clinic

Austin, Texas, United States

Site Status

Countries

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United States

References

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Adams CB, Johnston WH, Deulofeut H, Leader J, Rhodes R, Yeiser M, Harris CL, Wampler JL, Hill RJ, Cooper T. Growth and tolerance of healthy, term infants fed lower protein extensively hydrolyzed or amino acid-based formula: double-blind, randomized, controlled trial. BMC Pediatr. 2021 Jul 21;21(1):323. doi: 10.1186/s12887-021-02617-z.

Reference Type DERIVED
PMID: 34289820 (View on PubMed)

Other Identifiers

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3383-1

Identifier Type: -

Identifier Source: org_study_id