Evaluation of Preterm Infants Fed Post-Discharge Preterm Infant Formula

NCT ID: NCT03991949

Last Updated: 2022-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-04

Study Completion Date

2022-11-16

Brief Summary

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This single-group study will assess growth and tolerance of infants fed a post-discharge preterm infant formula containing a prebiotic.

Detailed Description

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Conditions

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Infant Development

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Experimental Infant Formula

Ready-to-feed, milk-based formula

Group Type EXPERIMENTAL

Experimental Infant Formula

Intervention Type OTHER

Formula fed Ad libitum

Interventions

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Experimental Infant Formula

Formula fed Ad libitum

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Gestational age at birth less than 37 weeks
* Birth weight less than 3200 g (approximately 7 pounds)
* Postmenstrual age is 34 0/7 through 41 0/7 weeks at enrollment
* Parent(s) confirm their intention to feed their infant the study product as the sole source of nutrition for the duration of the study
* The currently-fed formula is a milk-based infant formula at a caloric density of ≤ 24 Cal/fl oz.
* Singleton, twin, or triplet births only.
* Parent(s) confirm their intention not to administer solid foods or juices to their infant from enrollment through the duration of the study, unless instructed otherwise by their healthcare professional.
* Participant's parent(s) has voluntarily signed and dated an ICF, approved by an IRB/IEC and provided HIPAA (or other applicable privacy regulation) authorization prior to any participation in the study.

Exclusion Criteria

* An adverse maternal, fetal or participant medical history that is thought by the investigator to have potential for effects on tolerance, growth, and/or development.
* Participant is taking and plans to continue taking medications, home remedies, herbal preparations, prebiotics or probiotics, rehydration solutions, or parenteral nutrition
* Participant is known to require elective surgery with hospitalization, other than uncomplicated outpatient surgery, during the course of the study.
* Participant is in another study that has not been approved as a concomitant study
* Participant has an allergy or intolerance to any ingredient in the study product
* Participant is currently receiving oxygen therapy
* Participant is currently receiving antibiotics
* Participant is currently receiving tube feedings
Minimum Eligible Age

34 Weeks

Maximum Eligible Age

41 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Abbott Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michelle Johnson, RDN, LD

Role: STUDY_CHAIR

Abbott Nutrition

Locations

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University of South Florida

Tampa, Florida, United States

Site Status

University of Louisville Research Foundation, Inc.

Louisville, Kentucky, United States

Site Status

University of Mississippi Medical Center

Jackson, Mississippi, United States

Site Status

MetroHealth Medical Center

Cleveland, Ohio, United States

Site Status

The Cleveland Pediatric Research Center, LLC

Middleburg Heights, Ohio, United States

Site Status

Women's Hospital at Renaissance - Doctors Hospital at Renaissance

Edinburg, Texas, United States

Site Status

Maximos Ob/Gyn

League City, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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AL35

Identifier Type: -

Identifier Source: org_study_id