A Study of the Effects of Fish Protein Intake on Glucose Regulation in Overweight and Obese Adults.

NCT ID: NCT01641055

Last Updated: 2022-04-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

93 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-07-31

Study Completion Date

2012-11-30

Brief Summary

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The purpose of this study is to compare the possible health benefits of intake of proteins from salmon, herring, cod and milk on glucose tolerance in overweight and obese adults. Overweight and obese subjects often have reduced glucose tolerance, and previous findings from a study on cod proteins suggested that glucose tolerance was improved.

Detailed Description

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Participants receive 2.5g protein per day for 8 weeks as tablets.

Conditions

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Obesity Overweight

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Salmon protein hydrolysate

Group Type EXPERIMENTAL

Salmon protein hydrolysate

Intervention Type DIETARY_SUPPLEMENT

2.5g salmon protein hydrolysate per day for 8wk.

Herring protein hydrolysate

Group Type EXPERIMENTAL

Herring protein hydrolysate

Intervention Type DIETARY_SUPPLEMENT

2.5g herring protein hydrolysate per day for 8wk.

Cod protein

Group Type SHAM_COMPARATOR

Cod protein

Intervention Type DIETARY_SUPPLEMENT

2.5g cod protein per day for 8wk.

Milk protein

Group Type PLACEBO_COMPARATOR

Milk protein

Intervention Type DIETARY_SUPPLEMENT

2.5g milk protein per day for 8wk.

Interventions

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Salmon protein hydrolysate

2.5g salmon protein hydrolysate per day for 8wk.

Intervention Type DIETARY_SUPPLEMENT

Herring protein hydrolysate

2.5g herring protein hydrolysate per day for 8wk.

Intervention Type DIETARY_SUPPLEMENT

Cod protein

2.5g cod protein per day for 8wk.

Intervention Type DIETARY_SUPPLEMENT

Milk protein

2.5g milk protein per day for 8wk.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* BMI above 27 kg/m2
* healthy

Exclusion Criteria

* fasting blood glucose above 7 mM
* medication that affects blood glucose, lipids and inflammatory status
* pregnancy or breastfeeding
* allergies to fish or milk
* intentional weight loss and large fluctuation in body weight
* a high consumption of fish
* an extreme diet
* use of fish oil, n-3 or multivitamin supplements
Minimum Eligible Age

18 Years

Maximum Eligible Age

69 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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BlueProtein

UNKNOWN

Sponsor Role collaborator

NutriMar

UNKNOWN

Sponsor Role collaborator

University of Bergen

OTHER

Sponsor Role lead

Responsible Party

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Oddrun Anita Gudbrandsen

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Oddrun A Gudbrandsen, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Bergen

Locations

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Institute of Medicine, University of Bergen

Bergen, , Norway

Site Status

Countries

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Norway

References

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Hovland IH, Leikanger IS, Stokkeland O, Waage KH, Mjos SA, Brokstad KA, McCann A, Ueland PM, Slizyte R, Carvajal A, Mellgren G, Remman T, Hogoy I, Gudbrandsen OA. Effects of low doses of fish and milk proteins on glucose regulation and markers of insulin sensitivity in overweight adults: a randomised, double blind study. Eur J Nutr. 2020 Apr;59(3):1013-1029. doi: 10.1007/s00394-019-01963-0. Epub 2019 Apr 10.

Reference Type DERIVED
PMID: 30972484 (View on PubMed)

Other Identifiers

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2011/572

Identifier Type: -

Identifier Source: org_study_id

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