Medico-economic Comparison of Robot-assisted Radical Prostatectomy Versus Radical Prostatectomy Via Laparotomy

NCT ID: NCT01577836

Last Updated: 2025-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-11-26

Study Completion Date

2021-03-22

Brief Summary

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The main objective of the study is to estimate and compare the overall cost of care of patients over 60 months of follow-up between two groups: (1) patients undergoing robot-assisted radical prostatectomy using the Da Vinci system versus (2) patients undergoing robot-assisted radical prostatectomy via laparotomy.

The time horizon of the main objective changes to 60 months (due to the opportunity to access patient care consumption from the National Health Data System).

Detailed Description

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The secondary objectives of this research are to compare the following between the two groups:

* The actual cost of the surgical prostatectomy.
* Erectile function at 0, 1, 6, 12 and 24
* Oncological results at 1, 6, 12 and 24 months.
* Functional results at 0, 1, 6, 12 and 24 months.
* Quality of life at 0, 1, 6, 12 and 24 months.
* Complication rates at 1 and 24 months.

Conditions

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Prostatic Neoplasms

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Robotic assistance, Nîmes

The patients in this group will undergo robot-assisted radical prostatectomy at the University Hospital of Nîmes.

Group Type EXPERIMENTAL

Robot-assisted radical prostatectomy

Intervention Type PROCEDURE

Transperitoneal robot-assisted radical prostatectomy technique with the Da Vinci S

Laparotomy, Marseilles

The patients in this group will undergo radical prostatectomy via traditional laparotomy at the University Hospital Marseillles.

Group Type ACTIVE_COMPARATOR

Radical prostatectomy via laparotomy

Intervention Type PROCEDURE

Classic radical prostatectomy via open retropubic approach

Interventions

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Robot-assisted radical prostatectomy

Transperitoneal robot-assisted radical prostatectomy technique with the Da Vinci S

Intervention Type PROCEDURE

Radical prostatectomy via laparotomy

Classic radical prostatectomy via open retropubic approach

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* The patient must have given his informed and signed consent
* The patient must be insured or beneficiary of a health insurance plan
* The patient is available for 24 months of follow up
* Patient has localised prostate cancer
* Patient is eligible for radical prostatectomy

Exclusion Criteria

* The patient is participating in another study
* The patient is in an exclusion period determined by a previous study
* The patient is under judicial protection, under tutorship or curatorship
* The patient refuses to sign the consent
* It is impossible to correctly inform the patient
* Patient has a contraindication for a treatment necessary for this study
* Patients with psychiatric disorders
Minimum Eligible Age

45 Years

Maximum Eligible Age

75 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nīmes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Stéphane Droupy, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier Universitaire de Nîmes

Locations

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APHM - Hôpital de la Conception

Marseille, , France

Site Status

Clinique Beau Soleil

Montpellier, , France

Site Status

CHU de Nîmes - Hôpital Universitaire Carémeau

Nîmes, , France

Site Status

Countries

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France

References

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Bouvet S, Chkair S, Daures JP, Kabani S; OptiPRobot Study Group; Chevallier T, Lechevallier E, Droupy S. Robot-assisted approach versus open surgery and conventional laparoscopy for radical prostatectomy for prostate cancer: a micro-costing study. Health Econ Rev. 2025 Jul 5;15(1):55. doi: 10.1186/s13561-025-00652-5.

Reference Type RESULT
PMID: 40616606 (View on PubMed)

Other Identifiers

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2011-A01385-36

Identifier Type: OTHER

Identifier Source: secondary_id

AOI/2011/SD-03

Identifier Type: -

Identifier Source: org_study_id

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