Study of Robot-assisted Radical Prostatectomy Performed on Outpatient in Patients With Localized Prostate Cancer

NCT ID: NCT04319146

Last Updated: 2025-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-25

Study Completion Date

2025-12-31

Brief Summary

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The promoter propose a pilot study evaluating the feasability of robot-assisted radical prostatectomy on outpatient in patients with localized prostate cancer. This study will enrole a total of 20 patients over one center, followed for 1 month. The total study duration will be 15 months, including statistical analysis and publication.

Detailed Description

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The promoter propose to carry out a monocentric biomedical cohort study, interventional, falling within the scope of the law of the public health code of 9 August 2004, for a total duration of 15 months including statistical analysis and publication. This analysis will involve a total of 20 patients, followed for 1 month during which the study criteria will be evaluated.

The patients concerned are men over 18 years of age (with a favourable onco-geriatric opinion if \>70 years) with localised prostate cancer who are candidates for treatment by radical prostatectomy as first-line treatment. Patients must have a BMI of less than 35 kg/m², an ASA score of less than 3 and signed consent. Patients with a history of major abdominal surgery or sleep apnea syndrome will not be eligible.

The success rate of robot-assisted radical prostatectomy on an outpatient basis is defined by the absence of admission to a conventional inpatient unit within the first 24 hours after the procedure; the admission criterion being a Chung score of \>9 (street-readiness score) or a complication during the procedure that does not allow the patient to be discharged.

Concerning post-operative follow-up, on D+1, readmissions and complications will be sought by the RAAC coordination nurse. The patient will be seen again at 1 month, during which time possible consultations and/or readmissions for events related to the operation will be sought. Urinary incontinence will be investigated by completing the ICIQ continence questionnaire and early oncological findings (PAS and histology of the surgical specimen) will be evaluated. Patient satisfaction with ambulatory surgery will be assessed using the SSQ8 questionnaire collected at this visit.

Investigators are selected on the basis of their surgical experience for this technique and must have performed a minimum of 20 personal procedures.

Conditions

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Prostate Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Open label, monocentric study
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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robot-assisted radical prostatectomy

patient with a prostate cancer will be operated with a robot-assisted method. They will be supported on an outpatient basis

Group Type OTHER

robot-assisted radical prostatectomy

Intervention Type PROCEDURE

robot-assisted radical prostatectomy as first-line treatment

Interventions

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robot-assisted radical prostatectomy

robot-assisted radical prostatectomy as first-line treatment

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Men
* Older than 18 years old, if\> 70 years old, then patient having had a favorable onco-geriatric consultation (Balducci 2 and life expectancy\> 10 years)
* Patient with localized prostate cancer applying for radical prostatectomy treatment
* Patient accepting outpatient surgery
* Radical prostatectomy performed as first-line treatment
* BMI \<35
* ASA score \<3
* Accompanying person available (taxi authorized) to ensure return home
* Have quick access to a telephone line
* Patient who signed their informed consent
* Patient covered by social security or other health insurance

Exclusion Criteria

* History of major abdominal surgery
* History of pelvic radiotherapy
* History of major urogenital malformation
* Sleep apnea syndrome
* Taking the following drugs within 48 hours (Plavix®, anti-vitamin K / curative LMWH)
* Contraindication to ambulatory medical care
* Inability to understand and sign the informed consent and to complete the self-questionnaires
* Vulnerable people
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nice

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU de NICE Pasteur 2

Nice, CHU de Nice, France

Site Status

Countries

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France

Other Identifiers

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19-AOIP-03

Identifier Type: -

Identifier Source: org_study_id

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