Effects of Different Types of Exercise Interventions in Patients With Type 2 Diabetes

NCT ID: NCT01377558

Last Updated: 2011-06-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-04-30

Study Completion Date

2012-06-30

Brief Summary

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The purposes of the study are

* to determine which kind of supervised exercise intervention (aerobic endurance training versus strength endurance training versus combined aerobic endurance and strength endurance training) is more effective in improving the metabolic parameters in typ 2 diabetes patients
* to investigate what kind of intervention is more successful in reduction of concomitant diseases and improving quality of life
* to assess what kind of intervention induces highest effects in long term persistence of these positive changes

Detailed Description

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Meta-analyses which evaluated the effects of structured exercise programs in patients with type 2 diabetes demonstrate that regular physical activity improves glycosylated haemoglobin (König et al.: Resistance Exercise and Type 2 Diabetes Mellitus, Deutsche Zeitschrift für Sportmedizin Jahrgang 62, Nr. 1 (2011): 5-9). Sigal et al. proved that either aerobic or resistance training alone improved glycemic control in type 2 diabetes, but the improvements are greatest with combined aerobic and resistance training (Sigal, RJ, et al.: Effects of Aerobic Training, Resistance Training, or Both on Glycemic Control in Type 2 Diabetes, Ann Intern Med. 2007 Sep 18;147(6):357-69).

Therefore, aim of the current study is to compare the effects of aerobic endurance training or resistance endurance training or the combination of aerobic endurance training and resistance endurance training in diabetes type 2 patients without any other lifestyle or dietary interventions.

Conditions

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Type 2 Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Aerobic endurance training intervention

Aerobic endurance training

Group Type EXPERIMENTAL

Aerobic endurance training intervention

Intervention Type OTHER

The aerobic endurance training group will use cardiovascular training devices

week 1-4: 15 minutes warm up (group) 15 minutes intervention at 80-100% vAT two times per week

week 5-13: 15 minutes warm up (group) 30 minutes intervention at 95-110% vAT two times per week

week 14-26: 15 minutes warm up (group) 45 minutes intervention at 95-110% vAT two times per week

Strength endurance training intervention

Strength endurance training

Group Type EXPERIMENTAL

Strength endurance training intervention

Intervention Type OTHER

The strength endurance training intervention group will perform eight exercises on weight machines (Milon circuit training- 60 seconds activity, 30 seconds break)

week 1-4: 15 minutes warm up (group) 1 session resistance training intensity 3 (Buskies) two times per week

week 5-13: 15 minutes warm up (group) 2 sessions resistance training intensity 5 (Buskies) two times per week

week 14-26: 15 minutes warm up (group) 3 sessions resistance training intensity 5 (Buskies) two times per week

Combined training intervention

Combined aerobic endurance training and strength endurance training intervention

Group Type EXPERIMENTAL

Combined aerobic endurance and strength endurance training

Intervention Type OTHER

week 1-4: 15 minutes warm up (group) 15 minutes intervention at 80-100% vAT once per week and 15 minutes warm up (group) 1 session resistance training intensity 3 (Buskies) once per week

week 5-13: 15 minutes warm up (group) 15 minutes intervention at 95-110% vAT and 1 session resistance training intensity 5 (Buskies) two times per week

week 14-26: 15 minutes warm up (group) 30 minutes intervention at 95-110% vAT and 1 session resistance training intensity 5 (Buskies) once a week and 15 minutes warm up (group) 15 minutes intervention at 95-110% vAT and 2 sessions resistance training intensity 5 (Buskies) once a week

Control group

control group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Aerobic endurance training intervention

The aerobic endurance training group will use cardiovascular training devices

week 1-4: 15 minutes warm up (group) 15 minutes intervention at 80-100% vAT two times per week

week 5-13: 15 minutes warm up (group) 30 minutes intervention at 95-110% vAT two times per week

week 14-26: 15 minutes warm up (group) 45 minutes intervention at 95-110% vAT two times per week

Intervention Type OTHER

Strength endurance training intervention

The strength endurance training intervention group will perform eight exercises on weight machines (Milon circuit training- 60 seconds activity, 30 seconds break)

week 1-4: 15 minutes warm up (group) 1 session resistance training intensity 3 (Buskies) two times per week

week 5-13: 15 minutes warm up (group) 2 sessions resistance training intensity 5 (Buskies) two times per week

week 14-26: 15 minutes warm up (group) 3 sessions resistance training intensity 5 (Buskies) two times per week

Intervention Type OTHER

Combined aerobic endurance and strength endurance training

week 1-4: 15 minutes warm up (group) 15 minutes intervention at 80-100% vAT once per week and 15 minutes warm up (group) 1 session resistance training intensity 3 (Buskies) once per week

week 5-13: 15 minutes warm up (group) 15 minutes intervention at 95-110% vAT and 1 session resistance training intensity 5 (Buskies) two times per week

week 14-26: 15 minutes warm up (group) 30 minutes intervention at 95-110% vAT and 1 session resistance training intensity 5 (Buskies) once a week and 15 minutes warm up (group) 15 minutes intervention at 95-110% vAT and 2 sessions resistance training intensity 5 (Buskies) once a week

Intervention Type OTHER

Other Intervention Names

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aerobic endurance training Strength endurance training

Eligibility Criteria

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Inclusion Criteria

* diagnoses of type 2 diabetes (ADA criteria)
* admitted diabetes treatments will be diet and oral hypoglycemic agents

Exclusion Criteria

* sports intervention \>60 minutes per week
* medical conditions
* preproliferative or proliferative retinopathy
* instable coronary heart disease
* inability to perform the scheduled physical activity programs
* acute clinically significant intercurrent diseases
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hannover Medical School

OTHER

Sponsor Role collaborator

University of Giessen

OTHER

Sponsor Role lead

Responsible Party

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Department of Sports Medicine Giessen

Principal Investigators

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Andree Hillebrecht, Dr. med.

Role: PRINCIPAL_INVESTIGATOR

University of Giessen

Locations

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University of Giessen

Giessen, Hesse, Germany

Site Status

Sportpark Zwickau, Glauchau, Meerane

Zwickau, Saxony, Germany

Site Status

Countries

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Germany

Other Identifiers

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Gi-03-2011

Identifier Type: -

Identifier Source: org_study_id

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