Aerobic Training, Aerobic-resistance Training and Glucose Profile (CGMS) in Type 2 Diabetes

NCT ID: NCT00887094

Last Updated: 2011-08-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-06-30

Study Completion Date

2011-04-30

Brief Summary

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Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

Detailed Description

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Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

Conditions

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Diabetes Mellitus, Type 2 Treatment Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Aerobic exercise

One bout of aerobic physical training will be performed on a cycle ergometer for 50 min

Group Type EXPERIMENTAL

Acute aerobic exercise

Intervention Type BEHAVIORAL

Aerobic exercise (on a cycle ergometer, for 50 min)

Aerobic-resistance exercise

One bout of aerobic-resistance physical training will be performed on a cycle ergometer added by a strenght training for 50 min (total)

Group Type EXPERIMENTAL

Acute aerobic-resistance exercise

Intervention Type BEHAVIORAL

Aerobic-resistance exercise (on a cycle ergometer plus strength training, for 50 min in total)

Interventions

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Acute aerobic exercise

Aerobic exercise (on a cycle ergometer, for 50 min)

Intervention Type BEHAVIORAL

Acute aerobic-resistance exercise

Aerobic-resistance exercise (on a cycle ergometer plus strength training, for 50 min in total)

Intervention Type BEHAVIORAL

Other Intervention Names

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There are no other names There are no other names

Eligibility Criteria

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Inclusion Criteria

* Type 2 diabetic patients treated with diet and metformin, 35-65 years old

Exclusion Criteria

* Type 1 diabetic patients
* Treatment with insulin or sulphonylureas or glitazones
* Proliferative retinopathy
* Severe autonomic neuropathy
* Coronary artery disease
* Baseline fasting plasma glucose\>200 mg/dl
* Peripheral artery disease
* Amputation
* Heart failure
* Diabetic nephropathy
* Renal failure
Minimum Eligible Age

35 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital de Clinicas de Porto Alegre

OTHER

Sponsor Role lead

Responsible Party

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Hospital de Clinicas de Porto Alegre

Principal Investigators

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Beatriz Schaan, PhD

Role: PRINCIPAL_INVESTIGATOR

Hospital de Clinicas de Porto Alegre

Locations

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Hospital de Clinicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil

Site Status

Countries

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Brazil

References

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Figueira FR, Umpierre D, Casali KR, Tetelbom PS, Henn NT, Ribeiro JP, Schaan BD. Aerobic and combined exercise sessions reduce glucose variability in type 2 diabetes: crossover randomized trial. PLoS One. 2013;8(3):e57733. doi: 10.1371/journal.pone.0057733. Epub 2013 Mar 11.

Reference Type DERIVED
PMID: 23536769 (View on PubMed)

Figueira FR, Umpierre D, Ribeiro JP, Tetelbom PS, Henn NT, Esteves JF, Schaan BD. Accuracy of continuous glucose monitoring system during exercise in type 2 diabetes. Diabetes Res Clin Pract. 2012 Dec;98(3):e36-9. doi: 10.1016/j.diabres.2012.09.033. Epub 2012 Oct 4.

Reference Type DERIVED
PMID: 23041227 (View on PubMed)

Other Identifiers

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08-180

Identifier Type: -

Identifier Source: org_study_id

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