Comparing the Effects of Different Types of Exercise on Glucose Handling
NCT ID: NCT06217679
Last Updated: 2024-02-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
24 participants
INTERVENTIONAL
2018-05-01
2019-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
NONE
Study Groups
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Control Oral Glucose Tolerance Test
This visit will include a baseline OGTT to be used as a pre-exercise baseline measure for each of the arms. Participants will then consume a 75g glucose beverage (Trutol, Thermo Scientific) and blood samples will be drawn at 0, 10, 20, 30, 45, 60, 75, 90 and 120 minutes post consumption.
Control Oral Glucose Tolerance Test
control oral glucose tolerance test
Mixed Exercise
exercise performed in randomized order
High intensity interval exercise (HIIE)
Participants performed a High intensity interval exercise (HIIE) bout which includes 10 x 1 min at 90% maximum heart rate (HRmax) with 5 min warm up and 5 min cool down at 50watts (low state steady cycling). 90mins following the exercise bout participants will undergo another oral glucose tolerance test.
Control Oral Glucose Tolerance Test
control oral glucose tolerance test
Mixed Exercise
exercise performed in randomized order
Moderate intensity continuous exercise (MICE)
Participants performed a Moderate intensity continuous exercise (MICE) bout which includes 30 min at 65% maximal aerobic capacity (VO2max). 90mins following the exercise bout participants will undergo another oral glucose tolerance test.
Control Oral Glucose Tolerance Test
control oral glucose tolerance test
Mixed Exercise
exercise performed in randomized order
Low-load, high-repetition resistance exercise (LL-HR)
Participants performed a Low-load, high-rep resistance exercise (LL-HR) bout which includes a whole body resistance exercise bout, 3 sets at 30% maximum strength (1RM) for leg press, knee extension, hamstring curl, lat pulldown, shoulder press, chest press, 20-25 reps, last set to failure. 90mins following the exercise bout participants will undergo another oral glucose tolerance test.
Control Oral Glucose Tolerance Test
control oral glucose tolerance test
Mixed Exercise
exercise performed in randomized order
Interventions
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Control Oral Glucose Tolerance Test
control oral glucose tolerance test
Mixed Exercise
exercise performed in randomized order
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Are pregnant, or suspect that they may be pregnant, or nursing
* Inability to complete the single exercise sessions.
* Regularly participate in cardiovascular (\>3 sessions/week) or resistance training (\>2 sessions/week) exercise.
* Have an allergy to local anesthetic (or family history of allergy)
* Have undergone a barium swallow or an infusion of a contrast agent in the past 3 weeks
* Are taking prescription anti-coagulant or anti-platelet medications (e.g., warfarin, heparin, clopidogrel)
* Inability to exercise as suggested by the get active questionnaire (GAQ)
* BMI \> 27 kg/m2
18 Years
30 Years
ALL
Yes
Sponsors
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University of Waterloo
OTHER
Responsible Party
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Locations
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University of Waterloo
Waterloo, Ontario, Canada
Countries
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References
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Beaudry KM, Surdi JC, Pancevski K, Tremblay C, Devries MC. Greater glycemic control following low-load, high-repetition resistance exercise compared with moderate-intensity continuous exercise in males and females: a randomized control trial. Appl Physiol Nutr Metab. 2024 Jul 1;49(7):943-955. doi: 10.1139/apnm-2023-0353. Epub 2024 Mar 22.
Other Identifiers
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ORE #22477
Identifier Type: -
Identifier Source: org_study_id
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