Exercise Type That Faster Reduces Postprandial Glycemia.

NCT ID: NCT04846751

Last Updated: 2022-11-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

11 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-01

Study Completion Date

2024-09-10

Brief Summary

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It is well established that a bout of 50 min of continuous moderate intensity exercise, improves insulin sensitivity up to 48 hours after the bout. However, it is less well known, what is the exercise type more efficient to buffer the elevations in blood glucose elicited by carbohydrate ingestion. The purpose of this study is to elucidate if intervalic exercise is superior to continous on improving postprandial glycemic control.

Detailed Description

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Carbohydrate oxidation, glucose and insulin blood concentrations, isotopically measured rate of appearance of endogenous and exogenous glucose will be measured in 4 ocassions.

Participants will undergo in a cross-over randomized fashion the following trials:

1. Exercise pedalling during 50 min at 60% of their VO2max followed by an oral glucose tolerance test (OGTT).
2. Exercise pedalling during 50 min in a hot environment (33ÂșC) at 60% of their VO2max followed by an oral glucose tolerance test (OGTT).
3. Exercise pedalling during 50 min using intervalic bouts averaging 60% of VO2max followed by an oral glucose tolerance test (OGTT).
4. No exercise, followed by an oral glucose tolerance test (OGTT).

Conditions

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Glucose, High Blood Exercise-Induced Hyperinsulinism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Study composed of 4 trials, full-crossover, administered in a randomized order with the inclusion of a control trial.
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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AEROBIC EXERCISE

50 min of aerobic exercise by pedaling a cycleergometer at 60% of VO2max

Group Type ACTIVE_COMPARATOR

TYPE OF EXERCISE (OR REST)

Intervention Type BEHAVIORAL

continous exercise in normal temperature, continous exercise in hot environment, intervallic exercise in normal temperature.

PLACEBO REST

No exercise, resting during 50 min.

Group Type PLACEBO_COMPARATOR

TYPE OF EXERCISE (OR REST)

Intervention Type BEHAVIORAL

continous exercise in normal temperature, continous exercise in hot environment, intervallic exercise in normal temperature.

Interventions

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TYPE OF EXERCISE (OR REST)

continous exercise in normal temperature, continous exercise in hot environment, intervallic exercise in normal temperature.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Participant must be capable and willing to provide consent, understand, instructions and protocols.
* Minimal fitness level to be able to complete 50 min of continous exercise at a moderate intensity.

Exclusion Criteria

* Smokers
* Pregnancy
* Any non-controlled medical condition which could influence results or could be worsened by exercise
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Castilla-La Mancha

OTHER

Sponsor Role lead

Responsible Party

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Ricardo Mora

Director of the Exercise Lab at Toledo

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ricardo Mora-Rodriguez, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Castilla-La Mancha

Locations

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University of Castilla-La Mancha (Exercise Physiology Lab)

Toledo, , Spain

Site Status

Countries

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Spain

Other Identifiers

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PID2020-116159RB-I00

Identifier Type: -

Identifier Source: org_study_id

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