Perception of Blood Sugar Variations During Physical Activity in Healthy Subjects and Type 1 Diabetes Patients

NCT ID: NCT05357534

Last Updated: 2022-05-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-06-01

Study Completion Date

2023-02-01

Brief Summary

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Type 1 diabetes is an autoimmune disease with absence of insulin secretion. Blood sugar is a physiological variable that reflets for blood glucose concentration. Blood sugar level fluctuates, especially during physical activity.

Sports activity would increase insulin sensitivity, improve lifestyle and, by extension, promote glycemic balance. However, glycemic balance will be disturbed by physical activity with higher risk of hypoglycemia and hyperglycemia.

Moreover, hypoglycemia and hyperglycemia will impact body functions. Perceptions of blood sugar variations during physical exercise and their influences on sports performance have not been studied, whether in type 1 diabetes patients or healthy subjects.

Detailed Description

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The aim of the study is to evaluate the perception of blood sugar variations in healthy subjects and type 1 diabetes patients during physical activity

Conditions

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Type 1 Diabetes

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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"Type 1 diabetes" group

"type 1 diabetes" group: patients with type 1 diabetes

Group Type EXPERIMENTAL

Physical activity

Intervention Type OTHER

Physical activity: 10 km run on a treadmill

"healthy" group

"healthy" group : subjects without type 1 diabetes

Group Type ACTIVE_COMPARATOR

Physical activity

Intervention Type OTHER

Physical activity: 10 km run on a treadmill

Interventions

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Physical activity

Physical activity: 10 km run on a treadmill

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Type 1 diabetics diagnosed more than 3 years ago and controlled (an HbA1c of less than 8%) for "type 1 diabetes" group
* without diabetes for "healkthy" group
* Male
* Aged 18 to 65
* Body Mass Index less than 30 kg/m2
* regular running (at least 30 minutes per week and at least one 10-km run per year for the previous 2 years)
* Agreeing to participate in the study

Exclusion Criteria

* Physical injury
* beta blockers treatment
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Université de Reims Champagne-Ardenne

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Philippe JOLY, MCU-HDR

Role: CONTACT

0326918822 ext. +33

Coralie BARBE, MD

Role: CONTACT

0326918822 ext. +33

Other Identifiers

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2022-RIPH_002_GLYSPORT

Identifier Type: -

Identifier Source: org_study_id

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