Contrast Echocardiography in Non-ST Elevation Myocardial Infarction
NCT ID: NCT01122069
Last Updated: 2025-06-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
110 participants
OBSERVATIONAL
2008-03-31
2009-07-31
Brief Summary
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Early invasive treatment has been found cost-effective in intermediate and high-risk NSTEMI patients and current guidelines recommend use of the Thrombolysis in Myocardial Infarction (TIMI) risk score to identify patients who will benefit from early intervention due to high risk of new infraction and cardiovascular death. However, new research has suggested that TIMI risk score may not always identify patients with severe angiographic disease.
The purpose of this study was to assess if contrast echocardiography could be used to identify NSTEMI patients with angiographically severe disease independent of their TIMI risk score.
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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Contrast echocardiography
110 patients with acute non-ST elevation myocardial infarct were examined with contrast echocardiography prior to coronary angiography.
Perflutren Lipid Microsphere ultrasound contrast
Perflutren Lipid Microsphere ultrasound contrast 0.01 ml/kg administered as intravenous bolus
Interventions
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Perflutren Lipid Microsphere ultrasound contrast
Perflutren Lipid Microsphere ultrasound contrast 0.01 ml/kg administered as intravenous bolus
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* mechanical prosthetic heart valve
* severly reduced pulmonary function
18 Years
ALL
No
Sponsors
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Haukeland University Hospital
OTHER
University of Bergen
OTHER
Responsible Party
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Eva Gerdts
Professor of Cardiology
Principal Investigators
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Mai Tone Lønnebakken, MD
Role: PRINCIPAL_INVESTIGATOR
University of Bergen, Bergen, Norway
Locations
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Department of Heart Disease, Haukeland University Hospital
Bergen, , Norway
Countries
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References
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Eskerud I, Gerdts E, Nordrehaug JE, Lonnebakken MT. Global Coronary Artery Plaque Area is Associated with Myocardial Hypoperfusion in Women with Non-ST Elevation Myocardial Infarction. J Womens Health (Larchmt). 2015 May;24(5):367-73. doi: 10.1089/jwh.2014.4920. Epub 2015 Feb 18.
Lonnebakken MT, Nordrehaug JE, Gerdts E. No gender difference in the extent of myocardial ischemia in non-ST elevation myocardial infarction. Eur J Prev Cardiol. 2014 Jan;21(1):123-9. doi: 10.1177/2047487312454107. Epub 2012 Jul 2.
Other Identifiers
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REK237.07
Identifier Type: OTHER
Identifier Source: secondary_id
MCE-NSTEMI
Identifier Type: -
Identifier Source: org_study_id
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