Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
50 participants
OBSERVATIONAL
2025-11-25
2027-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Spontaneous coronary artery dissection (SCAD)
Subject has a history of spontaneous coronary artery dissection (SCAD)
Stress Echocardiography with Contrast
Stress Echocardiography with Contrast will be used to assess heart function and blood flow response to stressors.
Healthy Subjects
Subjects are healthy with no significant medical history
Stress Echocardiography with Contrast
Stress Echocardiography with Contrast will be used to assess heart function and blood flow response to stressors.
Interventions
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Stress Echocardiography with Contrast
Stress Echocardiography with Contrast will be used to assess heart function and blood flow response to stressors.
Eligibility Criteria
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Inclusion Criteria
* Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history
Exclusion Criteria
* Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine.
* Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®.
* Pregnant.
* Unable to interrupt breastfeeding.
* Within 3 months of a heart attack.
* Severe aortic stenosis.
* Severe, uncontrolled hypertension (\>200/110 mmHg at baseline).
18 Years
ALL
Yes
Sponsors
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National Heart, Lung, and Blood Institute (NHLBI)
NIH
Mayo Clinic
OTHER
Responsible Party
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Marysia Tweet
Principal Investigator
Principal Investigators
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Marysia Tweet, M.D., M.S.
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic
Locations
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Mayo Clinic
Rochester, Minnesota, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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24-002318
Identifier Type: -
Identifier Source: org_study_id
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