Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents
NCT ID: NCT00889876
Last Updated: 2023-04-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
26 participants
INTERVENTIONAL
2009-02-28
2015-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
TREATMENT
NONE
Study Groups
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Metformin
Metformin group
2000 mg/day for one year
Exercise
Exercise
3 times/week with a personal coach for one year. Endurance training.
Interventions
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Metformin group
2000 mg/day for one year
Exercise
3 times/week with a personal coach for one year. Endurance training.
Eligibility Criteria
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Inclusion Criteria
* Obesity according to gender and age specific BMI (Cole 2000)
* Reduced nocturnal systolic blood pressure fall (\< 10%)
* Signed informed consent by patient and parents
Exclusion Criteria
* Insulin dependent diabetes mellitus
* Patient on medications that are contraindicated during Metformin treatment
* Pregnancy
* Mental or physical conditions limiting the ability to participate
13 Years
19 Years
ALL
No
Sponsors
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Maria Sandberg Westerstahl
OTHER
Responsible Party
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Maria Sandberg Westerstahl
PhD
Principal Investigators
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Claude Marcus, Professor
Role: PRINCIPAL_INVESTIGATOR
Karolinska Institutet
Locations
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Karolinska Institutet, Karolinska University Hospital Huddinge
Stockholm, , Sweden
Countries
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Other Identifiers
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2008-000461-28
Identifier Type: -
Identifier Source: org_study_id
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