Investigation of Exercise Training-Induced Myokines and Adipolkines in Humans

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-12-15

Study Completion Date

2020-02-01

Brief Summary

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The purpose of this study is to find out whether exercise training leads to changes in the blood that are produced by exercised muscles and if these changes produce new hormones that affect the body's regulation of sugar and body weight.

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Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Single Group Assignment

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Experimental Exercise-Training Intervention

Subjects will undergo a 10-week aerobic exercise protocol.

Group Type EXPERIMENTAL

Exercise Intervention

Intervention Type OTHER

10 Week aerobic exercise training

Interventions

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Exercise Intervention

10 Week aerobic exercise training

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

\- Age between 18-35. Body mass index (BMI) must be ≥18.5 and ≤27 kg/m2. HbA1c values ≤5.7%

Exclusion Criteria

* Age \<18 and \>50
* HbA1c ≥ 5.7%; heart or lung disease
* acute systemic infection accompanied by fever, body aches, or swollen lymph glands
* BMI \> 27 kg/m2
* current dieting or weight loss efforts
* current pregnancy or breastfeeding
* known history of HIV/AIDS; cancer
* biochemical evidence of renal or hepatic dysfunction; renal or liver disease demyelinating diseases such as multiple sclerosis or amyotrophic lateral sclerosis
* recent blood donation
* clinical history of stroke
* hypertension (systolic \> 140 mmHg or diastolic \> 90 mmHg)
* type 1 or 2 diabetes; inability to exercise at 50% of predicted heart rate (HR) reserve at baseline
* Participants taking beta-blockers Participants who screen positive for The American Heart Association's contraindications to exercise testing

Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes