Action of Caffeinated and Decaffeinated Espresso on Autonomic Function

NCT ID: NCT00576030

Last Updated: 2010-07-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

77 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-01-31

Study Completion Date

2008-10-31

Brief Summary

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More than 80% of the population in the USA consume coffee each day. However there not many studies on change of heart rate variability and placebo effects after consumption of coffee.

In our study we aim to test the following hypotheses:

1. Habitual caffeinated espresso coffee drinkers show an increase in blood pressure, heart rate variability and parasympathetic activity (high frequency band) of the heart.
2. Non-habitual caffeinated espresso coffee drinkers show an increase of blood pressure. The heart rate variability and the parasympathetic activity of the heart will decrease.
3. Caffeinated or decaffeinated espresso induces comparable changes in habitual or non-habitual coffee drinkers.

Detailed Description

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Conditions

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Influence of Espresso on Heart Rate Variability

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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H

habitual coffee drinkers

Group Type OTHER

hab cof with water

Intervention Type OTHER

habitual coffee drinker provided with water

hab cof with dec espresso

Intervention Type OTHER

habitual coffee drinkers given decaffeinated espresso

hab cof with caf espresso

Intervention Type OTHER

habitual coffee drinkers given caffeinated espresso

N

non-habitual coffee drinkers

Group Type OTHER

non-hab cof with water

Intervention Type OTHER

non-habitual coffee drinkers given water

non-hab cof with dec espresso

Intervention Type OTHER

non-habitual coffee drinkers given decaffeinated espresso

non-hab cof with caf espresso

Intervention Type OTHER

non-habitual coffee drinkers given caffeinated espresso

Interventions

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hab cof with water

habitual coffee drinker provided with water

Intervention Type OTHER

hab cof with dec espresso

habitual coffee drinkers given decaffeinated espresso

Intervention Type OTHER

hab cof with caf espresso

habitual coffee drinkers given caffeinated espresso

Intervention Type OTHER

non-hab cof with water

non-habitual coffee drinkers given water

Intervention Type OTHER

non-hab cof with dec espresso

non-habitual coffee drinkers given decaffeinated espresso

Intervention Type OTHER

non-hab cof with caf espresso

non-habitual coffee drinkers given caffeinated espresso

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18- 50 years old, healthy

Exclusion Criteria

* Medication, obese(BMI \> 30)
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Dept of Psychosomatic Medicine and Psychotherapy, Benjamin Franklin Campus, Charité,Berlin

Locations

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Department of Psychosomatic Medicine and Psychotherapy, Charité University

Berlin, , Germany

Site Status

Countries

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Germany

Other Identifiers

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EA4/061/06

Identifier Type: -

Identifier Source: secondary_id

EA4/061/06

Identifier Type: -

Identifier Source: org_study_id

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