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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06977087 | RECRUITING | NA
58 Participants

The Efficacy of Prospective Mental Imagery in Enhancing Approach Motivation Among Socially Anxious Individuals

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-04
Completion: 2026-01-31
Conditions
Social Anxiety Social Phobia
Interventions
BEHAVIORAL
No Results Yet
NCT06976216 | RECRUITING | PHASE3
586 Participants

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-14
Completion: 2028-09-11
Conditions
Alzheimer's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06976203 | RECRUITING | PHASE3
586 Participants

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-21
Completion: 2028-09-11
Conditions
Alzheimer's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06973187 | RECRUITING | PHASE3
500 Participants

A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-09-04
Completion: 2028-04-17
Conditions
Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
NCT06963801 | RECRUITING | NA
100 Participants

DBT-P Treatment Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-06
Completion: 2026-12-31
Conditions
Emotion Dysregulation
Interventions
BEHAVIORAL
No Results Yet
NCT06959706 | RECRUITING | PHASE1
50 Participants

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-07
Completion: 2026-09-30
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06959264 | COMPLETED | NA
70 Participants

Effect of Virtual Reality Goggles on Anxiety, Comfort and Complications in Patients Undergoing Transrectal Ultrasound-guided Prostate Biopsy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-28
Completion: 2025-12-15
Conditions
Prostate Biopsy
Interventions
OTHER
No Results Yet
NCT06957028 | RECRUITING | NA
6000 Participants

CGM for the Early Detection and Management of Hyperglycemia in Pregnancy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-27
Completion: 2027-11-27
Conditions
Gestational Diabetes Mellitus in Pregnancy
Interventions
OTHER
No Results Yet
NCT06951711 | RECRUITING | PHASE3
274 Participants

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-13
Completion: 2026-11-02
Conditions
Bipolar Disorder Type I With Mania or Mania With Mixed Features
Interventions
DRUG OTHER
No Results Yet
NCT06943872 | RECRUITING | PHASE3
630 Participants

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-11
Completion: 2029-09-30
Conditions
Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
NCT06943859 | RECRUITING | PHASE2
50 Participants

Ketamine for Opioid Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-01-31
Completion: 2028-08-31
Conditions
Opioid Use Disorder
Interventions
DRUG
No Results Yet
NCT06942702 | NOT_YET_RECRUITING | NA
44 Participants

Efficacy of Genicular Block on Total Knee Arthroplasty Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-12-20
Completion: 2026-10-20
Conditions
Total Knee Anthroplasty Genicular Nerves Block
Interventions
DRUG
No Results Yet
NCT06936943 | RECRUITING | PHASE2
14 Participants

ONO-4538 Study in Patients With Richter's Transformation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-11-19
Completion: 2029-07-31
Conditions
Richter's Transformation
Interventions
DRUG
No Results Yet
NCT06934967 | RECRUITING | PHASE3
12 Participants

Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-10-28
Completion: 2031-11-19
Conditions
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions
DRUG
No Results Yet
NCT06932809 | RECRUITING | EARLY_PHASE1
90 Participants

Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-09
Completion: 2030-04-30
Conditions
Tauopathies
Interventions
DRUG DIAGNOSTIC_TEST BEHAVIORAL
No Results Yet
NCT06932302 | RECRUITING | NA
24 Participants

At-Home Neuromodulation for Female Sexual Dysfunction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-10-15
Completion: 2027-10-31
Conditions
Female Sexual Dysfunction
Interventions
DEVICE
No Results Yet
NCT06929273 | RECRUITING | PHASE3
450 Participants

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-18
Completion: 2028-06-13
Conditions
Bipolar Disorder Type I With Mania
Interventions
DRUG
No Results Yet
NCT06927973 | COMPLETED | NA
30 Participants

Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-30
Completion: 2025-12-19
Conditions
Chest Pain Shortness of Breath
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06925724 | RECRUITING | PHASE2
50 Participants

A Study of Ivonescimab in People With Endometrial and Cervical Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-04
Completion: 2027-04-30
Conditions
Endometrial Cancer Cervical Cancer
Interventions
DRUG
No Results Yet
NCT06925022 | ACTIVE_NOT_RECRUITING | NA
30 Participants

Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: The ADVICE Protocol Study (Phase 1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-15
Completion: 2025-06-30
Conditions
Multiple Sclerosis (MS) - Relapsing-remitting
Interventions
OTHER
No Results Yet
NCT06912724 | RECRUITING
80 Participants

Pediatric Neuroimaging

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-21
Completion: 2026-05-01
Conditions
Neurogimaging
No Results Yet
NCT06910358 | RECRUITING | PHASE3
150 Participants

Study of Bitopertin in Participants With EPP or XLP (APOLLO)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-04
Completion: 2026-10-31
Conditions
Erythropoietic Protoporphyria (EPP) X-Linked Protoporphyria (XLP)
Interventions
DRUG
No Results Yet
NCT06909422 | NOT_YET_RECRUITING | NA
100 Participants

Mobile Thinking Intervention: A Inital Test

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-05-31
Completion: 2028-08-31
Conditions
Schizophrenia Clinical High Risk for Psychosis (CHR)
Interventions
BEHAVIORAL
No Results Yet
NCT06908317 | COMPLETED | NA
26 Participants

Teaching the Getting Up From the Floor Among Long-Term Care Facility Residents

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-14
Completion: 2025-10-17
Conditions
Mobility Difficulty Exercise ELDERLY PEOPLE
Interventions
OTHER
No Results Yet
NCT06907472 | ACTIVE_NOT_RECRUITING | NA
106 Participants

Diabetes Management for Primary Healthcare Centers.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-09-15
Completion: 2026-06-15
Conditions
Type 2 Diabetes Mellitus (T2DM)
Interventions
DRUG
No Results Yet
NCT06906328 | RECRUITING | NA
248 Participants

MEthylphenidate in ADHD - Addiction(s) Comorbidity: Value of Adding a Cognitive Remediation Program to Improve Short- and Medium-term Therapeutic Response

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-12-11
Completion: 2028-12-11
Conditions
ADHD-add
Interventions
BEHAVIORAL
No Results Yet
NCT06904274 | RECRUITING | PHASE3
207 Participants

Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-11-24
Completion: 2027-05-03
Conditions
Endometrial Hyperplasia
Interventions
COMBINATION_PRODUCT DRUG
No Results Yet
NCT06902519 | RECRUITING | PHASE1
75 Participants

Study of GS-0151 in Participants With Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-14
Completion: 2027-03-31
Conditions
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
NCT06901362 | COMPLETED
401 Participants

Seroprevalence and Vaccination Rate of Hepatitis B Virus and Varicella-zoster Virus Among Medical Students Under Immunizing Program

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-01
Completion: 2025-08-31
Conditions
Healthy Healthy Adult
No Results Yet
NCT06899022 | RECRUITING | NA
138 Participants

Attention and Eye Movement in Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-09-22
Completion: 2028-02-29
Conditions
Essential Tremor Parkinson's Disease (PD)
Interventions
OTHER
No Results Yet
NCT06891755 | RECRUITING | NA
250 Participants

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-15
Completion: 2027-09-30
Conditions
COPD Emphysema
Interventions
DEVICE OTHER
No Results Yet
NCT06888817 | RECRUITING | PHASE3
408 Participants

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-19
Completion: 2028-07-31
Conditions
Radiation Necrosis High Grade Glioma (III or IV) Brain Metastasases Radiation Toxicity Radiation Effect Radiation Injury Radiation Injuries
Interventions
DRUG
No Results Yet
NCT06887192 | RECRUITING | PHASE2
300 Participants

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-08-15
Completion: 2027-02-28
Conditions
Psychosis Associated With Alzheimer's Disease
Interventions
DRUG
No Results Yet
NCT06883240 | RECRUITING
40 Participants

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-29
Completion: 2026-11-01
Conditions
Von Willebrand Disease, Type 3
Interventions
DRUG
No Results Yet
NCT06873581 | RECRUITING | PHASE3
266 Participants

Pivotal Study of Voro Urologic Scaffold

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-18
Completion: 2027-02-01
Conditions
Radical Prostatectomy Stress Urinary Incontinence (SUI)
Interventions
DEVICE
No Results Yet
NCT06870383 | RECRUITING | NA
66 Participants

Erector Spinae Block Versus Combined Pecto-intercostal and Recto-intercostal Fascial Plane Block in Cardiac Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-20
Completion: 2026-03-20
Conditions
Erector Spinae Plane Block Pecto-intercostal Fascial Plane Block Recto-intercostal Fascial Plane Block Cardiac Surgery
Interventions
DRUG
No Results Yet
NCT06863402 | RECRUITING | PHASE2
32 Participants

Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-02-15
Completion: 2029-04-01
Conditions
Richter Syndrome Diffuse Large B-Cell Lymphoma Chronic Lymphocytic Leukemia
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER
No Results Yet
NCT06863337 | RECRUITING | NA
100 Participants

Glucose Pattern in Infertile Women Receiving Assisted Reproduction Using Continuous Glucose Monitoring

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-26
Completion: 2026-06-30
Conditions
Infertility Female
Interventions
DEVICE
No Results Yet
NCT06850805 | RECRUITING | PHASE3
84 Participants

Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-28
Completion: 2028-03-31
Conditions
Chronic Rhinosinusitis Without Nasal Polyps
Interventions
DRUG
No Results Yet
NCT06849596 | RECRUITING | NA
780 Participants

Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-12-01
Completion: 2028-09-30
Conditions
Neonatal Resuscitation Apnea Neonatal
Interventions
DEVICE
No Results Yet
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