MedDataX Logo

Clinical Trials

Showing trials with last updates posted in 2025.

NCT05379166 | ACTIVE_NOT_RECRUITING | PHASE2
33 Participants

Venetoclax and Azacitidine for Treatment of Therapy Related or Secondary Myelodysplastic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-06-23
Completion: 2026-01-15
Conditions
Secondary Myelodysplastic Syndrome Therapy-Related Myelodysplastic Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT05352672 | ACTIVE_NOT_RECRUITING | PHASE3
1546 Participants

Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-07-14
Completion: 2026-03-16
Conditions
Melanoma
Interventions
DRUG
No Results Yet
NCT05350072 | ACTIVE_NOT_RECRUITING | PHASE3
276 Participants

Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-07-28
Completion: 2025-05-07
Conditions
Sjogren Syndrome
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05349214 | ACTIVE_NOT_RECRUITING | PHASE3
506 Participants

Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-08-04
Completion: 2025-05-13
Conditions
Sjogren Syndrome
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05347095 | ACTIVE_NOT_RECRUITING | PHASE3
288 Participants

A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-09-27
Completion: 2027-03-25
Conditions
Fistulizing Crohns Disease Perianal Crohns Disease
Interventions
DRUG
No Results Yet
NCT05342753 | COMPLETED | NA
22 Participants

Safety and Effectiveness of Restylane® Kysse for Lip Augmentation in Chinese Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-06-13
Completion: 2024-10-25
Conditions
Lip Augmentation
Interventions
DEVICE
Results Available
NCT05337618 | RECRUITING | PHASE2
72 Participants

Improving Neurotrauma by Depolarization Inhibition With Combination Therapy (INDICT)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-12-16
Completion: 2026-09-01
Conditions
Traumatic Brain Injury
Interventions
DIAGNOSTIC_TEST COMBINATION_PRODUCT
No Results Yet
NCT05320367 | NOT_YET_RECRUITING | PHASE1/PHASE2
80 Participants

A Study of Inhaled Cannabidiol in Healthy Occasional Cannabis Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-09-30
Completion: 2027-10-31
Conditions
Cannabis
Interventions
DRUG
No Results Yet
NCT05318924 | COMPLETED | PHASE1/PHASE2
26 Participants

Effects of Ghrelin Administration on Dopamine and Effort

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-02-21
Completion: 2024-08-06
Conditions
Major Depressive Disorder
Interventions
DRUG OTHER
No Results Yet
NCT05317416 | ACTIVE_NOT_RECRUITING | PHASE3
811 Participants

Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-03-25
Completion: 2027-08-04
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05304585 | RECRUITING | PHASE3
205 Participants

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-08-04
Completion: 2030-06-30
Conditions
Embryonal Rhabdomyosarcoma Fusion-Negative Alveolar Rhabdomyosarcoma Spindle Cell/Sclerosing Rhabdomyosarcoma
Interventions
PROCEDURE DRUG BIOLOGICAL RADIATION
No Results Yet
NCT05288543 | TERMINATED | PHASE1
63 Participants

A Study of Orally Administered IPG7236 in Healthy Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-04-07
Completion: 2023-03-31
Conditions
Atopic Dermatitis
Interventions
DRUG OTHER
No Results Yet
NCT05284513 | ENROLLING_BY_INVITATION | NA
532 Participants

Collaborative Approach to Reach Everyone With Familial Hypercholesterolemia (CARE-FH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-09-09
Completion: 2027-01-31
Conditions
Familial Hypercholesterolemia
Interventions
BEHAVIORAL
No Results Yet
NCT05271409 | RECRUITING | PHASE3
152 Participants

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-08-30
Completion: 2025-11-20
Conditions
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
Interventions
DRUG OTHER
No Results Yet
NCT05268289 | RECRUITING | PHASE2
240 Participants

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-08-10
Completion: 2026-03-30
Conditions
Lupus Nephritis
Interventions
DRUG
No Results Yet
NCT05258435 | ACTIVE_NOT_RECRUITING
131 Participants

Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2022-02-09
Completion: 2028-04-30
Conditions
Cervical Disc Disease Degenerative Disc Disease
Interventions
DEVICE
No Results Yet
NCT05241860 | ACTIVE_NOT_RECRUITING | PHASE2
79 Participants

Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-11-21
Completion: 2025-09-29
Conditions
Castration-Sensitive Prostate Carcinoma Metastatic Prostate Carcinoma Stage IV Prostate Cancer AJCC v8 Stage IVA Prostate Cancer AJCC v8 Stage IVB Prostate Cancer AJCC v8
Interventions
OTHER
No Results Yet
NCT05235165 | RECRUITING | PHASE3
250 Participants

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-04-01
Completion: 2031-03-31
Conditions
Metastatic Malignant Neoplasm in the Lung Metastatic Osteosarcoma Osteosarcoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT05228275 | ACTIVE_NOT_RECRUITING
549 Participants

Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2022-04-08
Completion: 2027-09-30
Conditions
COVID-19 Infection Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm
Interventions
PROCEDURE OTHER
No Results Yet
NCT05218655 | COMPLETED | PHASE3
101 Participants

A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-06-22
Completion: 2025-04-15
Conditions
Inherited Mitochondrial Disease
Interventions
DRUG
Results Available
NCT05202093 | COMPLETED | NA
129 Participants

Efficacy of Two Sonic Toothbrushes in Reducing Extrinsic Tooth Stain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-03-05
Completion: 2022-07-15
Conditions
Tooth Bleaching
Interventions
DEVICE
Results Available
NCT05199688 | RECRUITING | PHASE3
8 Participants

A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-31
Completion: 2027-03-31
Conditions
Neuromyelitis Optica Spectrum Disorder NMOSD
Interventions
DRUG
No Results Yet
NCT05193396 | RECRUITING | PHASE4
100 Participants

Hydrocortisone and Placebo in Patients With Symptoms of Adrenal Insufficiency After Cessation of Glucocorticoid Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-02-01
Completion: 2026-01-31
Conditions
Adrenal Insufficiency Polymyalgia Rheumatica (PMR) Giant Cell Arteritis (GCA)
Interventions
DRUG
No Results Yet
NCT05187429 | RECRUITING | PHASE1/PHASE2
42 Participants

Low Dose Nivolumab in Adults Living With HIV on Antiretroviral Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-01-24
Completion: 2029-01-31
Conditions
HIV I Infection
Interventions
DRUG
No Results Yet
NCT05174780 | COMPLETED | NA
159 Participants

Myopia Control With a Innovative Spectacle Lens

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-12-29
Completion: 2025-10-20
Conditions
Myopia
Interventions
DEVICE
No Results Yet
NCT05173844 | COMPLETED | NA
128 Participants

Digital Sleep Therapy for Older Adults With Cognitive Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-11-10
Completion: 2025-07-01
Conditions
Insomnia Type; Sleep Disorder Cognitive Impairment
Interventions
OTHER
No Results Yet
NCT05172973 | RECRUITING | NA
200 Participants

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-11-22
Completion: 2026-12-31
Conditions
Aortic Valve Insufficiency Aortic Valve Stenosis
Interventions
DEVICE
No Results Yet
NCT05171686 | COMPLETED | PHASE4
49 Participants

Diuretics and Volume Overload in Early CKD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-02-01
Completion: 2025-10-02
Conditions
Chronic Kidney Disease Hypertension
Interventions
DRUG
No Results Yet
NCT05167045 | COMPLETED
20 Participants

A Pilot Study for the Brain Health Support Program

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2021-11-15
Completion: 2022-04-29
Conditions
Dementia Mild Cognitive Impairment Subjective Cognitive Impairment Pre-dementia Dementia Prevention
Interventions
BEHAVIORAL
No Results Yet
NCT05152524 | ACTIVE_NOT_RECRUITING | NA
168 Participants

Distal Ischemic Stroke Treatment With Adjustable Low-profile Stentriever

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-03-25
Completion: 2025-12-31
Conditions
Ischemic Stroke Neovascularization
Interventions
DEVICE
No Results Yet
NCT05126277 | RECRUITING | PHASE3
462 Participants

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-07-14
Completion: 2027-06-22
Conditions
Lupus Nephritis
Interventions
DRUG
No Results Yet
NCT05124119 | COMPLETED
65 Participants

Strategies to Enhance Recruitment and Retention of Black Individuals Into Clinical Trials for Substance Use Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2022-04-01
Completion: 2022-12-01
Conditions
Substance Use Disorders
No Results Yet
NCT05123196 | COMPLETED | PHASE2
156 Participants

Exploratory Study of MT-8554 in Subjects With Painful Diabetic Peripheral Neuropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-11-16
Completion: 2022-11-01
Conditions
Painful Diabetic Peripheral Neuropathy
Interventions
DRUG
No Results Yet
NCT05120570 | COMPLETED | PHASE1/PHASE2
16 Participants

PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-03-17
Completion: 2024-09-19
Conditions
Acute Leukemia Myelodysplastic Syndromes Myeloproliferative Neoplasm Lymphoma
Interventions
DRUG
Results Available
NCT05119296 | ACTIVE_NOT_RECRUITING | PHASE2
12 Participants

Phase II Trial of Pembrolizumab in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-02-15
Completion: 2025-05-16
Conditions
Thyroid Cancer
Interventions
DRUG
No Results Yet
NCT05117307 | NOT_YET_RECRUITING | NA
60 Participants

Comparison of Transversalis Fascia Plane Block and Erector Spinae Plane Blocks in Cesarean Section

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-20
Completion: 2026-06-15
Conditions
Pain Postoperative Pain
Interventions
DRUG
No Results Yet
NCT05094336 | RECRUITING | PHASE1/PHASE2
649 Participants

A Study of AMG 193 in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-02-01
Completion: 2026-07-02
Conditions
Advanced MTAP-null Solid Tumors
Interventions
DRUG
No Results Yet
NCT05089227 | RECRUITING | PHASE2
72 Participants

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-02-03
Completion: 2028-08-31
Conditions
Prolonged Anticoagulation Venous Thromboembolic Disease Autoimmune Hemolytic Anemia
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05081245 | ACTIVE_NOT_RECRUITING | PHASE2
150 Participants

ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-09-13
Completion: 2026-10-31
Conditions
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT05080764 | ACTIVE_NOT_RECRUITING | PHASE2
126 Participants

Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Moderate to Severe Acne Vulgaris With Photodynamic Therapy in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-12-10
Completion: 2025-08-22
Conditions
Acne Vulgaris
Interventions
COMBINATION_PRODUCT
No Results Yet
Previous
Sorted by latest updates
Next
Showing 40 trials per page