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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07136428 | NOT_YET_RECRUITING | PHASE1/PHASE2
42 Participants

Asciminib in HER2+ Breast Cancer Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2026-02-28
Completion: 2030-11-01
Conditions
HER2+ Metastatic Breast Cancer
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT07134088 | RECRUITING | PHASE1/PHASE2
104 Participants

A Study of Subcutaneous Blinatumomab in Children With R/R and and MRD+ B-Cell Precursor Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-12-08
Completion: 2028-12-05
Conditions
Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia Minimal Residual Disease + B-Cell Acute Lymphoblastic Leukemia
Interventions
DRUG
No Results Yet
NCT07132411 | RECRUITING | NA
400 Participants

Talk With Me Baby: Leveraging Well-Child Care to Enhance the Early Home Language Environment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-12-31
Completion: 2029-03-31
Conditions
Child Language Language Delay Developmental Milestones
Interventions
BEHAVIORAL
No Results Yet
NCT07130123 | RECRUITING | NA
120 Participants

Endotracheal Suctionning During Positive Pressure Extubation in ICU

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-10-03
Completion: 2027-09-30
Conditions
Mechanical Ventilation With Oral Intubation Weaning Invasive Mechanical Ventilation Oxygen Saturation Measurement Rox Index Extubation
Interventions
PROCEDURE
No Results Yet
NCT07128914 | RECRUITING | PHASE1
32 Participants

A Clinical Study of GO306 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-07-31
Completion: 2026-12-31
Conditions
Solid Tumor Malignancies
Interventions
DRUG
No Results Yet
NCT07127770 | COMPLETED | PHASE1
9 Participants

A Study to Understand How the Body Processes [14C]PF-07104091 in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-28
Completion: 2025-10-08
Conditions
Healthy Adults
Interventions
DRUG
No Results Yet
NCT07127198 | COMPLETED | NA
24 Participants

Tolerance and Appetite Reduction of a Nutritional Solution With Intragastric Gelation Properties

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-05-22
Completion: 2025-10-31
Conditions
Weight Management
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT07124000 | RECRUITING
100 Participants

DESTINY-PANTUMOUR04

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-18
Completion: 2028-03-30
Conditions
Esophageal Cancer Gall Bladder Cancer Gastrointestinal Stromal Tumour Head and Neck Cancer Liver Cancer Melanoma Mouth Cancer Nasopharangeal Cancer Neuroendocrine, Gastrointestinal Cancer Ovarian Cancer Pancreatic Cancer Prostate Cancer Renal Cell Carcinoma Salivary Gland Cancer Sarcoma Small Cell Lung Cancer Testicular Cancer Throat Cancer Thyroid Cancer Urethral Cancer Vaginal Cancer Vulvar Cancer Endometrial Cancer Adenocarcinoma (NOS) Anal Cancer Bladder Cancer Cervical Cancer
Interventions
DRUG
No Results Yet
NCT07120945 | RECRUITING | NA
70 Participants

Hugoâ„¢ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-28
Completion: 2026-01-31
Conditions
Uterine Fibroids (UF) Menstrual Disorders Adenomyosis of Uterus Endometriosis Uterine Prolapse Precancerous/Nonmalignant Condition Cervical Cancer Endometrial Cancer Ovarian Cancer
Interventions
DEVICE
No Results Yet
NCT07118254 | ACTIVE_NOT_RECRUITING | PHASE2
15 Participants

A PHASE II PROSPECTIVE RANDOMIZED DOUBLE-MASKED CROSSOVER STUDY ASSESSING THE SAFETY & EFFICACY OF RHPRG4 (450 μG/ML RECOMBINANT HUMAN PROTEOGLYCAN 4) COMPARED TO VEHICLE FOR THE TREATMENT OF OCULAR GRAFT-VERSUS-HOST DISEASE (OGVHD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-17
Completion: 2026-09-30
Conditions
Ocular Graft Versus Host Disease
Interventions
DRUG
No Results Yet
NCT07116759 | ACTIVE_NOT_RECRUITING
20 Participants

Head Stabilization of Healthy Volunteers

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2022-10-09
Completion: 2024-10-01
Conditions
Healthy
Interventions
DEVICE
Results Available
NCT07116525 | RECRUITING | NA
60 Participants

A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-15
Completion: 2026-09-30
Conditions
Scar-related Atrial Tachycardia Persistent Atrial Fibrillation Paroxysmal Atrial Fibrillation Ventricular Procedures Ventricular Tachycardia Ischemic Ventricular Tachycardia Non-ischemic Ventricular Tachycardia Cardiomyopathy Idiopathic Ventricular Tachycardia Premature Ventricular Contraction
Interventions
DEVICE
No Results Yet
NCT07115680 | COMPLETED
503 Participants

Where Did the Authors Work When They Conducted Their Clinical Pharmacology Studies?

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-15
Completion: 2025-11-04
Conditions
Scientific Collaboration in Clinical Pharmacology
Interventions
OTHER
No Results Yet
NCT07115043 | RECRUITING | PHASE1/PHASE2
60 Participants

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-07-29
Completion: 2029-10-02
Conditions
Melanoma Non-small Cell Lung Cancer Squamous Cell Carcinoma (Skin) Renal Cell Carcinoma Merkel Cell Carcinoma Triple Negative Breast Cancer Head and Neck Squamous Cell Carcinoma Gastric Cancer/Gastroesophageal Junction Cancer High Grade Serous Ovarian Carcinoma
Interventions
DRUG
No Results Yet
NCT07111481 | RECRUITING | NA
40 Participants

Effect of Music on Surgical Performance During Artificial Intelligence-Based Simulation Training

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-05
Completion: 2026-01-31
Conditions
Surgical Education
Interventions
BEHAVIORAL
No Results Yet
NCT07109154 | RECRUITING
200 Participants

DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2025-11-25
Completion: 2027-04-30
Conditions
Lung Neoplasms
No Results Yet
NCT07108244 | ENROLLING_BY_INVITATION | NA
43 Participants

Use of [18F]FET PET-MRI to Improve Detection of Pituitary Adenomas in Cushing's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-10-22
Completion: 2029-07-30
Conditions
Cushing Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07107737 | NOT_YET_RECRUITING | NA
250 Participants

Physician Engagement in EMS Transport Refusal Rates

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2026-01-31
Completion: 2026-08-31
Conditions
Refusal of Transport
Interventions
BEHAVIORAL
No Results Yet
NCT07105709 | RECRUITING | PHASE2
220 Participants

Open-label Extension Study in Participants With Early Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-14
Completion: 2028-09-01
Conditions
Alzheimer's Disease
Interventions
DRUG
No Results Yet
NCT07101939 | RECRUITING | PHASE2
120 Participants

A Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide Therapy (PROACT 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-06-23
Completion: 2027-03-31
Conditions
Obesity Muscle Loss
Interventions
DRUG
No Results Yet
NCT07098962 | COMPLETED | PHASE2/PHASE3
100 Participants

KinesioTaping for Thoracic Drain Support

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-15
Completion: 2025-12-12
Conditions
Primary Condition: Pain, Postoperative Associated Conditions: Cardiac Surgical Procedures, Thoracic Surgery
Interventions
OTHER DRUG
No Results Yet
NCT07093281 | NOT_YET_RECRUITING | PHASE4
25 Participants

Intranasal LAIV Mucosal Immunity Examination

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2026-02-28
Completion: 2026-04-30
Conditions
Impact of Vaccination
Interventions
BIOLOGICAL
No Results Yet
NCT07091526 | RECRUITING
168 Participants

Whether Control of Serum Uric Acid (SUA) Improves Survival After Pancreatic Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2025-07-29
Completion: 2026-12-29
Conditions
Serum Uric Acid
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07085611 | RECRUITING | NA
30 Participants

Neutralizing Power of Serum Antibodies - 2

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-22
Completion: 2030-08-22
Conditions
COVID-19 SARS-CoV-2 Viraemia Monkey Pox Vaccination Serum Mucosal Immunity
Interventions
OTHER
No Results Yet
NCT07084766 | COMPLETED | NA
200 Participants

The Variation in Uterine Flexion Angle Before and After Voiding in Parous Women.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-25
Completion: 2025-10-30
Conditions
Uterine Anteflexion Parous Women
Interventions
PROCEDURE
No Results Yet
NCT07084064 | ACTIVE_NOT_RECRUITING | NA
58 Participants

Families Moving Together Curriculum

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-06-05
Completion: 2026-05-31
Conditions
Physical Activities Families
Interventions
BEHAVIORAL
No Results Yet
NCT07082608 | RECRUITING | NA
74 Participants

Effect of Weight Loss From ESG Plus Lifestyle Changes vs. Lifestyle Changes Alone in Sleep Apnea Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-19
Completion: 2029-05-19
Conditions
OSA - Obstructive Sleep Apnea
Interventions
DEVICE OTHER
No Results Yet
NCT07075536 | ENROLLING_BY_INVITATION | NA
795 Participants

A Web-Based Tool to Help People With Health Conditions Make Contraceptive Decisions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-15
Completion: 2028-08-31
Conditions
Contraceptive Usage Contraceptive Behavior Chronic Disease Chronic Condition Chronic Conditions, Multiple
Interventions
BEHAVIORAL
No Results Yet
NCT07070986 | RECRUITING
62 Participants

Randomized, Single-blind Pilot Study Assessing the Effect of Cutaneous RESonance Stimulation SYMPAthetic and Parasympathetic Tone and Anxiety in Patients Admitted for Cardiac Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-30
Completion: 2027-03-03
Conditions
Anxiety
Interventions
PROCEDURE OTHER
No Results Yet
NCT07065994 | ACTIVE_NOT_RECRUITING | NA
60 Participants

The Effect of Virtual Reality Glasses Application on Pain and Anxiety Levels in Colorectal Surgery Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-01
Completion: 2025-12-31
Conditions
Colorectal Surgery Virtual Reality Nursing Care Pain Anxiety
Interventions
DEVICE
No Results Yet
NCT07063342 | RECRUITING | PHASE1
72 Participants

A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference Following Single Doses, and to Explore the Effect of Food After Multiple Doses of Selected Prototypes in Healthy Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-06-27
Completion: 2026-08-15
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT07063277 | RECRUITING | NA
142 Participants

Comparison of Oxygen Reserve Index and Spirometry in Predicting Respiratory Complications After Coronary Artery Bypass Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-07-05
Completion: 2025-12-12
Conditions
Coronary Arterial Disease (CAD) Coronary Artery Bypass Graft (CABG) Postoperative Pulmonary Complication
Interventions
DEVICE
No Results Yet
NCT07062965 | RECRUITING | PHASE3
400 Participants

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-05
Completion: 2027-07-22
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT07059702 | ACTIVE_NOT_RECRUITING
50 Participants

Why do People With Cerebral Palsy Often Feel Fatigued?

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2025-07-01
Completion: 2035-12-31
Conditions
Fatigue Intensity
Interventions
OTHER
No Results Yet
NCT07059299 | RECRUITING | PHASE1
18 Participants

A Phase Ib Trial Evaluating the Safety and Activity of Neoadjuvant Combination of Tislelizumab Plus FLOT for Resectable Esophagogastric Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-12-12
Completion: 2027-08-31
Conditions
Esophagogastric Junction Adenocarcinoma Gastric Adenocarcinoma Esophageal Adenocarcinoma Resectable Esophagogastric Adenocarcinoma Neoadjuvant Therapy
Interventions
DRUG
No Results Yet
NCT07059065 | RECRUITING | NA
316 Participants

FIBERGRAFT Aeridyan Posterolateral Fusion Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-26
Completion: 2026-03-01
Conditions
Degenerative Spine Disease
Interventions
DEVICE
No Results Yet
NCT07057583 | ENROLLING_BY_INVITATION
40 Participants

A Study of Carbon 13-based Deep Labelling of Bone Marrow Cells

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2025-02-01
Completion: 2027-12-31
Conditions
Monoclonal Gammopathy of Undetermined Significance (MGUS) Non-IgM Monoclonal Gammopathy of Undetermined Significance
Interventions
OTHER
No Results Yet
NCT07057531 | COMPLETED | NA
73 Participants

Tubeless VATS for Lung Cancer Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-07-25
Completion: 2025-12-05
Conditions
Lung Lung Cancer (NSCLC) VATS
Interventions
PROCEDURE
No Results Yet
NCT07052903 | RECRUITING | PHASE3
1250 Participants

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-07-02
Completion: 2030-05-28
Conditions
Transthyretin Amyloidosis With Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT07052006 | ACTIVE_NOT_RECRUITING | PHASE2
37 Participants

A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and Anemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-12-09
Completion: 2026-03-31
Conditions
Myelodysplastic Syndrome Anemia in Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
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