A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter

NCT ID: NCT07116525

Last Updated: 2025-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-15

Study Completion Date

2026-09-30

Brief Summary

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The purpose of this study is to assess the safety and feasibility of the investigational catheter for mapping the atrial and ventricular regions of the heart.

Detailed Description

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Conditions

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Scar-related Atrial Tachycardia Persistent Atrial Fibrillation Paroxysmal Atrial Fibrillation Ventricular Procedures Ventricular Tachycardia Ischemic Ventricular Tachycardia Non-ischemic Ventricular Tachycardia Cardiomyopathy Idiopathic Ventricular Tachycardia Premature Ventricular Contraction

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DEVICE_FEASIBILITY

Blinding Strategy

NONE

Study Groups

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Arrhythmia Mapping by a Paddle-shaped, High-density, Multi-electrode Mapping Catheter

Participants scheduled to have a clinically indicated catheter mapping and ablation procedure for management of a cardiac arrhythmias will undergo catheter mapping and ablation procedure using paddle-shaped, high-density, multi-electrode mapping catheter.

Group Type EXPERIMENTAL

Paddle-Shaped, High-Density, Multi-Electrode Mapping Catheter

Intervention Type DEVICE

High-density, multi-electrode mapping catheter will be used for the procedure.

Interventions

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Paddle-Shaped, High-Density, Multi-Electrode Mapping Catheter

High-density, multi-electrode mapping catheter will be used for the procedure.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with and candidate for clinically indicated catheter mapping and ablation procedure for the management of ventricular tachycardia, premature ventricular complex, atrial tachycardia or atrial fibrillation (participant having undergone a previous ablation procedure may be included)
* At least one episode of the targeted arrhythmia (ventricular tachycardia, premature ventricular complex, atrial tachycardia or atrial fibrillation) must have been documented by electrocardiogram (ECG), Holter, loop recorder, telemetry, implanted device, or transtelephonic monitoring within 12 months prior to enrollment
* Age 18 years or older
* Signed Patient Informed Consent Form (ICF)
* Able and willing to comply with all pre-, post-, and follow-up testing and requirements

Exclusion Criteria

* Study arrhythmia secondary to reversible cause, or secondary to electrolyte imbalance, thyroid disease, or non cardiac cause
* Patients requiring left atrial procedures: left atrial size greater than (\>) 55 millimeter (mm)
* Left ventricular ejection fraction(LVEF) less than or equal to (\<=) 25 percentage (%) for participants with ventricular arrhythmia
* LVEF \<= 40% for participants with atrial arrhythmia
* Documented intracardiac thrombus as detected on imaging within 24 hours prior to insertion of the investigational catheter
* Contraindication to anticoagulation (that is, heparin, warfarin, dabigatran)
* History of blood clotting or bleeding abnormalities (example hypercoagulable state)
* Myocardial infarction within the past 2 months (60 days)
* Documented thromboembolic event (including transient ischemic attack \[TIA\]) within the past 12 months (365 days)
* Uncontrolled heart failure or New York heart association (NYHA) function class IV
* Implanted with a pacemaker or intracardiac cardiac defibrillator or appendage closure device within the past 6 weeks (42 days)
* Patients with known untreatable allergy to contrast media
* Active illness or active systemic infection or sepsis
* Diagnosed atrial or ventricular myxoma, interatrial baffle or patch, tumor or other abnormality that precludes catheter introduction or manipulation
* Significant congenital anomaly or medical problem that in the opinion of the investigator would preclude enrollment in this study
* Participants that have ever undergone a percutaneous or surgical valvular cardiac procedure (that is, ventriculotomy, atriotomy, and valve repair or replacement and presence of a prosthetic valve)
* Participants that currently have Impella or equivalent devices on the procedure date or up to 7 days prior
* Any cardiac surgery within the past 60 days (2 months) (includes percutaneous coronary intervention \[PCI\])
* Atrial septal closure within the past 6 weeks (42 days)
* Presence of a condition that precludes vascular access
* Women who are pregnant (as evidenced by pregnancy test if pre-menopausal), lactating, or who are of childbearing age and plan on becoming pregnant during the course of the clinical investigation
* Categorized as vulnerable population and requires special treatment with respect to safeguards of well-being
* Concurrent enrollment in an investigational study evaluating another device or drug
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Biosense Webster, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Biosense Webster, Inc. Clinical Trial

Role: STUDY_DIRECTOR

Biosense Webster, Inc.

Locations

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AZ Sint-Jan

Bruges, , Belgium

Site Status RECRUITING

Jessa Ziekenhuis

Hasselt, , Belgium

Site Status RECRUITING

Hopital les Franciscaines of Nimes

Nîmes, , France

Site Status WITHDRAWN

CHU de Bordeaux - Hospital Haut-Leveque

Pessac, , France

Site Status RECRUITING

Chu Rennes Hopital Pontchaillou

Rennes, , France

Site Status RECRUITING

Vilnius University Hospital Santaros Clinics

Vilnius, , Lithuania

Site Status RECRUITING

Countries

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Belgium France Lithuania

Central Contacts

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Study Contact

Role: CONTACT

Phone: 844-434-4210

Email: [email protected]

Other Identifiers

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BWI202307

Identifier Type: OTHER

Identifier Source: secondary_id

BWI202307

Identifier Type: -

Identifier Source: org_study_id