Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery

NCT ID: NCT07327125

Last Updated: 2026-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-01-01

Study Completion Date

2028-03-01

Brief Summary

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This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.

Patients undergoing elective surgery with a midline abdominal incision will be randomly assigned to one of two groups: 1. Interrupted Closure Group: The surgical incision is closed using either metal clips (staples) or separate mattress sutures (individual stitches). 2. Subcuticular Sutures Group: The surgical incision is closed using continuous stitches placed under the skin surface (aesthetic stitching).

The main goal of the study is to determine whether the method of wound closure affects a patient's perception of their body image, cosmetic satisfaction, and levels of anxiety or depression.

Additionally, the study aims to prove that the subcuticular suture technique is safe and does not increase the risk of wound complications (such as infection or wound separation) compared to the other method.

Participants will be asked to complete questionnaires before surgery, and again at 1, 3 and 6 months after surgery to track changes in their feelings and satisfaction with the scar.

Detailed Description

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Midline abdominal incisions are common in gynecologic oncology, yet the optimal skin closure technique to minimize scar-related psychological distress remains unclear. While staples offer speed, subcuticular sutures may provide superior cosmetic results. This study aims to fill the gap in the literature regarding the specific impact of these closure methods on body image and patient-reported outcomes in gynecologic cancer patients, beyond standard wound complication rates.

Conditions

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Gynecologic Cancers Surgical Wound Closure Techniques Body Image

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This is a prospective, randomized, parallel-group study. Participants are stratified based on Body Mass Index (\<30 vs. ≥30 kg/m²), incision length (\<15 cm vs. ≥15 cm), and intra-operative frozen section pathology result (Benign vs. Malignant). Randomization is performed intra-operatively, immediately after the frozen section result is available.

Allocation uses a 1:1 ratio with permuted blocks of variable sizes (4, 6, 8) to ensure balanced assignment within each stratum. The randomization sequence was pre-generated using a fixed random seed (offline Excel file). Allocation concealment is maintained; the operating surgeon is blinded to future assignments and accesses the next allocation only after the patient is fully eligible.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Subcuticular Suture Group

Patients in this group will undergo skin closure using a continuous subcuticular suture technique with absorbable suture material.

Group Type EXPERIMENTAL

Continuous Subcuticular Suture

Intervention Type PROCEDURE

Surgical skin closure performed using a continuous technique with absorbable suture material.

Interrupted Closure Group

Patients in this group will undergo skin closure using interrupted techniques. The incision will be closed with either surgical staples (metal clips) or interrupted mattress sutures, depending on the standard practice.

Group Type ACTIVE_COMPARATOR

Interrupted Skin Closure

Intervention Type PROCEDURE

Surgical skin closure performed using interrupted techniques, specifically metal staples or interrupted mattress sutures.

Interventions

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Continuous Subcuticular Suture

Surgical skin closure performed using a continuous technique with absorbable suture material.

Intervention Type PROCEDURE

Interrupted Skin Closure

Surgical skin closure performed using interrupted techniques, specifically metal staples or interrupted mattress sutures.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Female participants aged 18 years or older.
* Patients scheduled for elective open gynecologic surgery for suspected or confirmed gynecologic malignancy.
* Surgery planned to be performed via a vertical midline laparotomy incision.
* Literate patients capable of reading, understanding, and completing the Body Image Scale (BIS) and Hospital Anxiety and Depression Scale (HADS).
* Patients who provide written informed consent to participate in the study.

Exclusion Criteria

* History of prior radiotherapy to the abdominal or pelvic region.
* Patients currently receiving chronic immunosuppressive therapy.
* Body Mass Index (BMI) less than 18 kg/m\^2 or greater than 40 kg/m\^2.
* Presence of cognitive impairment, dementia, or Alzheimer's disease.
* Major psychiatric disorders that prevent the patient from understanding or completing the questionnaires.
* Patients undergoing emergency surgery.
Minimum Eligible Age

17 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Başakşehir Çam & Sakura City Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Mahmut Yassa

Principal Investigator - Gynecologic Oncology Specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bora Taşpınar, MD

Role: PRINCIPAL_INVESTIGATOR

Başakşehir Çam & Sakura City Hospital

Central Contacts

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mahmut yassa, MD

Role: CONTACT

+90 539 663 54 84

Other Identifiers

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BCSSH-JINONK-01

Identifier Type: -

Identifier Source: org_study_id

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