Subcuticular Suture Versus Staples for Closure of the Skin After Caesarean Section.

NCT ID: NCT01217567

Last Updated: 2012-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-03-31

Study Completion Date

2012-01-31

Brief Summary

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The Purpose of this study is to compare two methods for closure of the skin after caesarean section on the same patient; staples and subcuticular sutures. The study is performed on two separate groups of patients: 1. Woman having cesarean section for the first time and have not previously had abdominal surgery through a lower abdominal transverse incision. 2. Woman, who have previously had a caesarean section done. The following parameters are registered:

1. An objective evaluation of the two ends of the scar 6 months postoperatively.
2. A patient evaluation of the two ends of the scar 6 months postoperatively.
3. The difference in pain in the two ends of the scar 1 day postoperatively (blinded).
4. The difference in pain in the two ends of the scar 7 days, 3 and 6 months postoperatively.
5. The rate of infection.

Detailed Description

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Conditions

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Cesarean Section Cicatrix

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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1st c-section, no previous lower abdominal surgery - s.l.

Group Type EXPERIMENTAL

Staples left, subcuticular suture right

Intervention Type PROCEDURE

Closure of the skin after cesarean section with staples on the left side of the wound and subcuticular suture on the right side.

Woman with previous ceasarean section - staples left

Group Type EXPERIMENTAL

Staples left, subcuticular suture right

Intervention Type PROCEDURE

Closure of the skin after cesarean section with staples on the left side of the wound and subcuticular suture on the right side.

1st c-section, no previous lower abdominal surgery

Group Type EXPERIMENTAL

Subcuticular suture left side and staples right

Intervention Type PROCEDURE

Closure of the skin after cesarean section with staples on the right side of the wound and subcuticular suture on the left side.

Woman with previous ceasarean section

Group Type EXPERIMENTAL

Subcuticular suture left side and staples right

Intervention Type PROCEDURE

Closure of the skin after cesarean section with staples on the right side of the wound and subcuticular suture on the left side.

Interventions

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Staples left, subcuticular suture right

Closure of the skin after cesarean section with staples on the left side of the wound and subcuticular suture on the right side.

Intervention Type PROCEDURE

Subcuticular suture left side and staples right

Closure of the skin after cesarean section with staples on the right side of the wound and subcuticular suture on the left side.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Woman having elective or level III caesarean section. Level III caesarean section is defined as being ordered more than 30 minutes before surgery is started.
* Woman who speak and understand Danish
* Woman who can give informed consent.

Exclusion Criteria

* Level I or II caesarean section (ordered less than 30 min. before surgery is started).
* Diabetics (this does not include gestational diabetes).
* Infection
* Regular treatment with immunosuppressives
* Alcohol or drug abuse
* Age under 18
* Chronic pain disease eg fibromyalgia, rheumatoid arthritis
* BMI over 35
* Previous abdominal surgery through lower transverse abdominal incision (only applicable to woman having caesarean section for the first time).
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Copenhagen

OTHER

Sponsor Role collaborator

Region Zealand

OTHER

Sponsor Role collaborator

Holbaek Sygehus

OTHER

Sponsor Role lead

Responsible Party

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Anna Aabakke

Anna Aabakke, M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Niels Jørgen Secher, Profesoor, M.D.

Role: STUDY_CHAIR

Department of Obstetrics, Hvidovre Hospital

Anna J. M. Aabakke, M.D.

Role: PRINCIPAL_INVESTIGATOR

Department of Gynaechology and Obstetrics, Holbæk Sygehus

Locations

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Department of Gynaechology and Obstetrics, Holbæk Sygehus

Holbæk, , Denmark

Site Status

Countries

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Denmark

References

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The CAESAR study: http://www.npeu.ox.ac.uk/caesar

Reference Type BACKGROUND

Jenkins TR. It's time to challenge surgical dogma with evidence-based data. Am J Obstet Gynecol. 2003 Aug;189(2):423-7. doi: 10.1067/s0002-9378(03)00587-8.

Reference Type BACKGROUND
PMID: 14520211 (View on PubMed)

CORONIS Trial Collaborative Group. The CORONIS Trial. International study of caesarean section surgical techniques: a randomised fractional, factorial trial. BMC Pregnancy Childbirth. 2007 Oct 22;7:24. doi: 10.1186/1471-2393-7-24.

Reference Type BACKGROUND
PMID: 18336721 (View on PubMed)

Altman AD, Allen VM, McNeil SA, Dempster J. Pfannenstiel incision closure: a review of current skin closure techniques. J Obstet Gynaecol Can. 2009 Jun;31(6):514-520. doi: 10.1016/S1701-2163(16)34213-X.

Reference Type BACKGROUND
PMID: 19646316 (View on PubMed)

Frishman GN, Schwartz T, Hogan JW. Closure of Pfannenstiel skin incisions. Staples vs. subcuticular suture. J Reprod Med. 1997 Oct;42(10):627-30.

Reference Type BACKGROUND
PMID: 9350017 (View on PubMed)

Gaertner I, Burkhardt T, Beinder E. Scar appearance of different skin and subcutaneous tissue closure techniques in caesarean section: a randomized study. Eur J Obstet Gynecol Reprod Biol. 2008 May;138(1):29-33. doi: 10.1016/j.ejogrb.2007.07.003. Epub 2007 Sep 6.

Reference Type BACKGROUND
PMID: 17825472 (View on PubMed)

Singer AJ, Arora B, Dagum A, Valentine S, Hollander JE. Development and validation of a novel scar evaluation scale. Plast Reconstr Surg. 2007 Dec;120(7):1892-1897. doi: 10.1097/01.prs.0000287275.15511.10.

Reference Type BACKGROUND
PMID: 18090752 (View on PubMed)

Rousseau JA, Girard K, Turcot-Lemay L, Thomas N. A randomized study comparing skin closure in cesarean sections: staples vs subcuticular sutures. Am J Obstet Gynecol. 2009 Mar;200(3):265.e1-4. doi: 10.1016/j.ajog.2009.01.019.

Reference Type BACKGROUND
PMID: 19254586 (View on PubMed)

Alderdice F, McKenna D, Dornan J. Techniques and materials for skin closure in caesarean section. Cochrane Database Syst Rev. 2003;(2):CD003577. doi: 10.1002/14651858.CD003577.

Reference Type BACKGROUND
PMID: 12804476 (View on PubMed)

Johnson A, Young D, Reilly J. Caesarean section surgical site infection surveillance. J Hosp Infect. 2006 Sep;64(1):30-5. doi: 10.1016/j.jhin.2006.03.020. Epub 2006 Jul 5.

Reference Type BACKGROUND
PMID: 16822582 (View on PubMed)

Cromi A, Ghezzi F, Gottardi A, Cherubino M, Uccella S, Valdatta L. Cosmetic outcomes of various skin closure methods following cesarean delivery: a randomized trial. Am J Obstet Gynecol. 2010 Jul;203(1):36.e1-8. doi: 10.1016/j.ajog.2010.02.001. Epub 2010 Apr 24.

Reference Type BACKGROUND
PMID: 20417924 (View on PubMed)

Aabakke AJM, Krebs L, Pipper CB, Secher NJ. Subcuticular suture compared with staples for skin closure after cesarean delivery: a randomized controlled trial. Obstet Gynecol. 2013 Oct;122(4):878-884. doi: 10.1097/AOG.0b013e3182a5f0c3.

Reference Type DERIVED
PMID: 24084548 (View on PubMed)

Other Identifiers

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SJ-162

Identifier Type: OTHER

Identifier Source: secondary_id

Cicatricestudiet

Identifier Type: -

Identifier Source: org_study_id

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