Sensory Distribution and Postoperative Analgesia of Ultrasound-Guided Interfascial Plane Blocks in Living Liver Donors

NCT ID: NCT07252063

Last Updated: 2025-11-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-11-01

Study Completion Date

2026-01-31

Brief Summary

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Living liver donor hepatectomy at our institution routinely includes ultrasound-guided interfascial plane blocks as part of postoperative analgesia. Although these blocks have become increasingly used in donor hepatectomy, their cutaneous sensory distributions and block-related dermatomal coverage have not been systematically evaluated, with only anecdotal reports available in the literature.

This prospective observational study aims to assess both the sensory blockade patterns and the early postoperative analgesic performance of interfascial plane blocks administered to living liver donors. Following surgery, all consenting donors receive the institution's standard block protocol. Cutaneous sensory mapping is performed in the post-anesthesia care unit (PACU) at the second postoperative hour. Pain intensity and analgesic requirements within the first 24 hours are also recorded.

The study is designed to provide objective data on the dermatomal coverage and postoperative analgesic effects of contemporary ultrasound-guided interfascial plane blocks used in living liver donor surgery.

Detailed Description

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Conditions

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Pain

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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interfascial plane block

Ultrasound-guided interfascial plane blocks are administered at the end of surgery. Block selection and needle entry points are determined according to the surgical incision line and the location of abdominal drains. All blocks are performed under real-time ultrasound guidance using the institution's standardized protocol.

Intervention Type OTHER

patient controlled analgesia device

Intravenous patient-controlled analgesia is initiated in the postoperative period according to the institution's standard protocol. PCA settings, opioid type, basal infusion (if applicable), and bolus doses follow routine clinical practice and are recorded for analysis. PCA use during the first 24 hours is monitored to assess postoperative analgesic requirements.

Intervention Type OTHER

cutaneus sensory mapping

Cutaneous sensory mapping is performed in the post-anesthesia care unit (PACU) at the second postoperative hour. Sensory blockade is assessed using a standardized pinprick test applied radially from medial to lateral directions. The borders of the blocked and unblocked regions are marked on the skin using a UV-visible dermatographic pen. Mapping is conducted over the mid-abdominal and lateral abdominal regions, and the total cutaneous coverage areas are subsequently calculated for analysis.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Adult living liver donors undergoing elective donor hepatectomy

Age 18 to 65 years

ASA physical status I-II

Patients who have received ultrasound-guided interfascial plane blocks as part of their postoperative analgesia

Ability to cooperate with postoperative sensory mapping procedures

Patients who agree to participate and provide written informed consent

Exclusion Criteria

Patients who refuse to participate or do not provide written informed consent

Patients who have not received any ultrasound-guided interfascial plane block

ASA physical status \> II

Presence of surgical incisions or wound complications preventing reliable sensory mapping

Prior major abdominal surgery that may alter cutaneous innervation patterns

Cognitive impairment limiting the ability to cooperate with sensory testing

Known psychiatric disorders (e.g., major depression, mania, schizophrenia) that may interfere with postoperative assessment

Local infection, skin disease, or dermatologic condition preventing accurate cutaneous mapping

Allergy or contraindication to local anesthetics used in the block
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bahçeşehir University

OTHER

Sponsor Role lead

Responsible Party

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Selma Basyigit

Department of Anesthesiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Bahcesehir Unişversity Medicalpark Goztepe hospital

Istanbul, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Selma Kahyaoglu

Role: CONTACT

+905053705332

Serkan Tulgar

Role: CONTACT

+905055423985

Facility Contacts

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Selma Kahyaoglu

Role: primary

Other Identifiers

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Liver mapping

Identifier Type: -

Identifier Source: org_study_id

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