External Oblique Intercostal Plane Block for Liver Transplantation Donors

NCT ID: NCT05890079

Last Updated: 2024-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

64 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-08

Study Completion Date

2024-01-17

Brief Summary

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Postoperative pain management is one of the important factors to improve rehabilitation and enhance recovery. External oblique intercostal plane block may be used for abdominal wall analgesia to provide effective analgesia for abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block and subcostal transversus abdominis plane block in living liver donors.

Researchers will compare the external oblique intercostal plane block group with subcostal transversus abdominis plane block to see if the external oblique intercostal plane block is effective for postoperative analgesia in living liver donors.

Detailed Description

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Patients scheduled for living donor hepatectomy will be separated into 2 groups: Subcostal Transversus Abdominis Plane Block Group and External Oblique Intercostal Plane Block Group. Patients in Subcostal Transversus Abdominis Plane Block will be performed subcostal transversus plane block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Patients in External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.

Conditions

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Liver Transplantation Donor Postoperative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Subcostal transversus abdominis plane block group

The patients in subcostal transversus abdominis plane block group will be received subcostal transversus abdominis plane block and patient controlled analgesia with morphine for postoperative analgesia

Group Type ACTIVE_COMPARATOR

Subcostal transversus abdominis plane block

Intervention Type OTHER

External oblique intercostal plane block will be administered at the end of the surgery and after skin closure.

External oblique intercostal plane block group

The patients in External oblique intercostal plane block group will be received external oblique intercostal plane block and patient controlled analgesia with morphine for postoperative analgesia

Group Type ACTIVE_COMPARATOR

External oblique intercostal plane block

Intervention Type OTHER

External oblique intercostal plane block will be administered at the end of the surgery and after skin closure. .

Interventions

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Subcostal transversus abdominis plane block

External oblique intercostal plane block will be administered at the end of the surgery and after skin closure.

Intervention Type OTHER

External oblique intercostal plane block

External oblique intercostal plane block will be administered at the end of the surgery and after skin closure. .

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 75 years
* Patients with American Society of Anesthesiology (ASA) physical status I-II
* Patients scheduled for a living donor hepatectomy

Exclusion Criteria

* Allergy to local anesthetics
* Coagulopathy
* Skin infection at the block area
* Advanced renal failure
* Chronic pain syndromes
* Alcohol or drug abuse
* Psychiatric disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istinye University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Taylan Sahin, M.D.

Role: PRINCIPAL_INVESTIGATOR

Istinye University

Locations

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Istinye University Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Sahin T, Kavakli AS, Eren E, Aydin A, Sahin NK, Tokac M, Dinckan A. Ultrasound-guided external oblique intercostal plane block versus subcostal transversus abdominis plane block for postoperative analgesia in living liver donors: A prospective randomized trial. J Clin Anesth. 2025 Sep;106:111971. doi: 10.1016/j.jclinane.2025.111971. Epub 2025 Aug 19.

Reference Type DERIVED
PMID: 40840080 (View on PubMed)

Other Identifiers

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anestezi2

Identifier Type: -

Identifier Source: org_study_id

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