Day Care in Robotic Surgery Hysterectomy. Investigate Quality of Life and Safety With Same Day Discharge After Robotic Hysterectomy for Patients With Benign and Malignant Disease. A Multicenter Randomized Study With 3 Hospitals in Stockholm Sweden.

NCT ID: NCT07233811

Last Updated: 2025-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-01-01

Study Completion Date

2028-01-31

Brief Summary

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Patients undergoing robotic assisted hysterectomy in three different hospitals in Stockholm will be randomized to day-care (going home the same day as the surgery) or admission (staying at least one night after surgery). The aim with this study is to investigate if patients in day-care recover as fast/faster as the other group that stays in the hospital. Both patients with benign disease and malign disease (endometrial cancer) will be included in the study.

Patients quality of life (QoL) will be measured before surgery and after surgery at day 3,7 and 30 with a questionnaire called Eq-5D-5L from Euroqol. The questionnaire is validated for postoperative QoL and widely used.

Complications due to surgery within the 30 first days after surgery will also be recorded in the two groups to make sure it is safe for the patients to go home the same day as their surgery.

Detailed Description

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The study is a multicenter randomized non-inferiority trial. Three hospitals will participate in the study, Södersjukhuset and Danderyds sjukhus for benign indications, and Karolinska Sjukhuset Solna in case of endometrial cancer. The experimental group consisting of patients undergoing same-day discharge, while the control group consisting of patients admitted overnight. The study will use a 1:1 randomization ratio between the experimental and the control group with stratification for malignant and benign cases, given that Karolinska University Hospital Solna only handles endometrial cancer cases, while the other two sites handle benign cases exclusively.

To measure Quality of Life, the validated Euroqol instrument EQ-5D-5L will be used. The EQ-5D-5L instrument is well validated and used in several studies. The literature support that a 5 points difference at the visaul analog scale (VAS) scale is significant for better/worse health QoL.

To measure patient satisfaction with the length of hospital stay and care given they will at day 30 receive an additional questionnaire, the "Quality in patent perspective" (QPP), which is a validated questionnaire in Swedish.

Conditions

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Hysterectomy Same Day Discharge Robotic Surgical Procedures

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Day care

The patient returns to home the same day as the surgery is performed (before midnight)

Group Type EXPERIMENTAL

Day care

Intervention Type OTHER

The patient return to home the same day as the surgery is performed.

Overnight stay

The patient stay at the hospital overnight after their surgery.

Group Type ACTIVE_COMPARATOR

Overnight stay

Intervention Type OTHER

The patient spend the night at the hospital and can not go home until the next morning.

Interventions

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Overnight stay

The patient spend the night at the hospital and can not go home until the next morning.

Intervention Type OTHER

Day care

The patient return to home the same day as the surgery is performed.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient that are planned to undergo total robotic hysterectomy with or without adnexal surgery at the three sites.
* Both benign conditions and endometrial cancer.
* All BMI groups and all uterus sizes.

Exclusion Criteria

* Age not over 75 years old,
* No company at home first night after surgery
* ASA class 3 that is not only because of high BMI.
* Simultaneous prolapse surgery/lymph node evacuation.
* Severe endometriosis or patients with chronic pain conditions that have a special pain regimen after surgery.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Karolinska Institutet

OTHER

Sponsor Role lead

Responsible Party

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Malin Brunes

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Malin Brunes, MD,PhD

Role: PRINCIPAL_INVESTIGATOR

Karolinska Institutet

Locations

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Södersjukhuset

Stockholm, , Sweden

Site Status RECRUITING

Danderyd Hospital

Stockholm, , Sweden

Site Status RECRUITING

Karolinska University hospital

Stockholm, , Sweden

Site Status RECRUITING

Countries

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Sweden

Central Contacts

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Emily Benér, MD

Role: CONTACT

+46705554427

Malin Brunes, MD, PhD

Role: CONTACT

+46722350385

Facility Contacts

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Emily Rebecka Benér, MD

Role: primary

+460705554427

Malin Brunes, MD, PhD

Role: backup

Ulrika Johannesson, MD, Docent

Role: primary

+460812355000

Emily Benér, MD

Role: backup

Vilhelm Mörlin, MD

Role: primary

+460812380000

Emily Benér, MD

Role: backup

+46705554427

Other Identifiers

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2023-05648-01

Identifier Type: -

Identifier Source: org_study_id

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