Laparoscopic Supracervical Hysterectomy Versus Total Laparoscopic Hysterectomy

NCT ID: NCT00734812

Last Updated: 2013-01-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

PHASE3

Study Classification

INTERVENTIONAL

Study Start Date

2008-05-31

Study Completion Date

2012-01-31

Brief Summary

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The purpose of this research study is to evaluate whether there is any difference in recovery time and return to normal activities following a laparoscopic supracervical hysterectomy (LSH) compared with total laparoscopic hysterectomy (TLH). Both types of hysterectomies are commonly performed at our institution.

Patients will be assigned by chance (like a coin toss) to have either a LSH or a TLH. Preoperatively, participants will complete a quality of life questionnaire (SF-36), a sexual function questionnaire (FSFI)and a 3 question questionnaire about urinary function (3IQ).

Following surgery participants will be asked to keep a diary of pain symptoms and use of narcotics. The diary will be filled out daily until patients have resumed normal activities from prior to the surgery. The SF-36 will be completed again 6 weeks following the original surgery.

6 months following surgery participants will receive a copy of the SF-36 and the FSFI in the mail. They will also be asked questions about urinary symptoms and persistent vaginal bleeding.

Detailed Description

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Conditions

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Gynecologic Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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1

Laparoscopic supracervical hysterectomy (LSH)

Group Type ACTIVE_COMPARATOR

Laparoscopic supracervical hysterectomy

Intervention Type PROCEDURE

Patients will be randomized to LSH (retaining the cervix) and TLH (cervix removal)

2

Total Laparoscopic Hysterectomy (TLH)

Group Type ACTIVE_COMPARATOR

Total laparoscopic hysterectomy

Intervention Type PROCEDURE

Patients will be randomized to either removal or retention of cervix

Interventions

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Laparoscopic supracervical hysterectomy

Patients will be randomized to LSH (retaining the cervix) and TLH (cervix removal)

Intervention Type PROCEDURE

Total laparoscopic hysterectomy

Patients will be randomized to either removal or retention of cervix

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Candidates for laparoscopic hysterectomy for benign indications

Exclusion Criteria

* Malignancy of the uterus, cervix or adnexa
* pre-malignant changes of the uterus, cervix or adnexa
* history of severe cervical dysplasia (CIN II or above)
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Brigham and Women's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jon I. Einarsson

Chief, Division of Minimally Invasive Gynecology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jon I. Einarsson, MD

Role: PRINCIPAL_INVESTIGATOR

Brigham and Women's Hospital

Locations

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Brigham and Women's Hospital

Boston, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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2007-P-002591/1

Identifier Type: -

Identifier Source: org_study_id

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